SCHEMBL1127228

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1126635	0.88	JAK3 (0.38)	FAAHNPC1RAB9AJAK3LMNA
	SCHEMBL1127213	0.86	NPC1 (0.39)	FAAHEPHX2HDAC4NPC1RAB9A
	SCHEMBL1988597	0.85	IL2 (0.41)	HDAC4LMNAALDH1A1MAPTSMN1; SMN2
	SCHEMBL1645643	0.82	L3MBTL1 (0.53)	FAAHEPHX2HDAC4NPC1RAB9A
	SCHEMBL1126812	0.81	ALDH1A1 (0.48)	NPC1RAB9ALMNAHTTALDH1A1
	SCHEMBL1127158	0.81	FAAH (0.42)	FAAHEPHX2HDAC4NPC1RAB9A
	SCHEMBL1126931	0.76	RAB9A (0.46)	NPC1RAB9ALMNAHTTALDH1A1
	SCHEMBL1126539	0.76	TRPV1 (0.40)	NPC1RAB9AHTTALDH1A1MAPT
	SCHEMBL1993111	0.75	ALDH1A1 (0.42)	NPC1RAB9ALMNAHTTALDH1A1
	SCHEMBL30235338	0.75	ALDH1A1 (0.42)	NPC1RAB9ALMNAHTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.