Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11279686 | 0.88 | HCAR3 (0.52) | HCAR3MAPTPKMPOLBALDH1A1 | |
| SCHEMBL11208114 | 0.84 | HCAR3 (0.47) | HCAR3MAPTPKMPOLBALDH1A1 | |
| SCHEMBL14334902 | 0.82 | MAPT (0.60) | HCAR3MAPTPKMPOLBALDH1A1 | |
| SCHEMBL29959789 | 0.82 | MAPT (0.60) | HCAR3MAPTPKMPOLBALDH1A1 | |
| SCHEMBL3655815 | 0.79 | PTGER4 (0.41) | HCAR3MAPTPKMPOLBALDH1A1 | |
| SCHEMBL1046521 | 0.77 | HCAR3 (0.58) | HCAR3MAPTPKMPOLBALDH1A1 | |
| SCHEMBL15239673 | 0.76 | MAPT (0.61) | HCAR3MAPTPKMPOLBALDH1A1 | |
| SCHEMBL11220359 | 0.76 | VCAM1 (0.43) | MAPTPOLBALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL11231775 | 0.76 | LMNA (0.42) | MAPTALDH1A1TDP1LMNAMAPK1 | |
| SCHEMBL11073590 | 0.75 | ALDH1A1 (0.37) | HCAR3MAPTALDH1A1TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344957-A | Benz-acyl-benzimidazole derivatives and antiallergic compositions | CIBA-GEIGY CORPORATION (US) | 1982-08-17 | — | — | US | disclosed |
| US-4213993-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1980-07-22 | — | — | US | disclosed |
| US-4141982-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1979-02-27 | — | — | US | disclosed |