Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL161795 | 0.71 | SMN1; SMN2 (0.49) | KDM4EHTTTSHRKMT2AMEN1 | |
| SCHEMBL5274120 | 0.69 | LMNA (0.67) | KDM4EHTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27571120 | 0.68 | NAAA (0.72) | HDAC3KMT2AMEN1SMN1; SMN2NAAA | |
| SCHEMBL5277697 | 0.67 | ABCG2 (0.62) | HTTMAPT | |
| SCHEMBL3092684 | 0.67 | ALDH1A1 (0.81) | HTTTSHRHDAC3KMT2AMEN1 | |
| SCHEMBL7345817 | 0.67 | KDM4E (0.53) | KDM4EHTTTSHRNAAAALDH1A1 | |
| SCHEMBL9257833 | 0.66 | MGLL (0.63) | HTTHDAC3KMT2AALDH1A1GAA | |
| SCHEMBL6900481 | 0.66 | MEN1 (0.42) | TSHRKMT2AMEN1POLB | |
| SCHEMBL11271239 | 0.66 | GPR35 (0.47) | KDM4EHTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1002854 | 0.66 | NAAA (0.86) | HTTTSHRHDAC3SMN1; SMN2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4364956-A | ASTHMA | LILLY INDUSTRIES LIMITED (GB) | 1982-12-21 | — | — | US | disclosed |