SCHEMBL1127934

SCHEMBL1127934

Cc1ccccc1C(=S)c1ccc([S])cc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
HTT P42858 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
MAPT P10636 2/20 0.37
KCNK3 O14649 1/20 0.36
KCNK9 Q9NPC2 1/20 0.36
HPGD P15428 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C19 P33261 1/20 0.36
POLB P06746 1/20 0.35
GAA P10253 1/20 0.35
ELANE P08246 1/20 0.35
CTNNB1 P35222 1/20 0.35
WNT3A P56704 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11757375 0.86 AKR1C3 (0.44) ALDH1A1SMN1; SMN2NPC1RAB9AMEN1
SCHEMBL31613189 0.86 AKR1C3 (0.44) ALDH1A1SMN1; SMN2NPC1RAB9AMEN1
SCHEMBL11757827 0.85 ALDH1A1 (0.49) ALDH1A1SMN1; SMN2NPC1RAB9AMAPT
SCHEMBL1127935 0.82 ALDH1A1 (0.37) ALDH1A1SMN1; SMN2NPC1RAB9AHTT
SCHEMBL8256708 0.80 TSHR (0.47) ALDH1A1SMN1; SMN2NPC1RAB9AHTT
SCHEMBL3281845 0.77 LMNA (0.42) ALDH1A1SMN1; SMN2NPC1RAB9AMEN1
SCHEMBL20546806 0.74 KMT2A (0.48) ALDH1A1SMN1; SMN2NPC1RAB9AMEN1
SCHEMBL30717265 0.74 CES2 (0.56) ALDH1A1SMN1; SMN2NPC1RAB9AMEN1
SCHEMBL28586350 0.72 MEN1 (0.42) ALDH1A1SMN1; SMN2HTTMEN1KMT2A
SCHEMBL1127542 0.72 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2NPC1RAB9AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12024579-B2 Curable liquid composition, particulate filler, and compound TOKYO OHKA KOGYO CO., LTD. (JP) 2024-07-02 US disclosed
CN-112470551-B Sealing agent for organic electroluminescent display element 电化株式会社 2024-05-14 CN disclosed
CN-113227159-B Composition and method for producing the same 电化株式会社 2024-04-19 CN disclosed
US-20240045330-A1 NEGATIVE PHOTOSENSITIVE COMPOSITION AND PATTERN FORMATION METHOD TOKYO OHKA KOGYO CO., LTD. (JP) 2024-02-08 US disclosed
CN-117510794-A Composition and method for producing the same 电化株式会社 2024-02-06 CN disclosed
CN-113272383-B Composition and method for producing the same 电化株式会社 2023-11-17 CN disclosed
CN-113227169-B Sealant, cured body, organic electroluminescent display device, and method for manufacturing device 电化株式会社 2023-10-31 CN disclosed
US-20230236505-A1 NEGATIVE PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMATION METHOD, AND LAMINATED FILM SAN-APRO LTD. (JP) 2023-07-27 US disclosed
CN-116018558-A Negative photosensitive resin composition, pattern forming method and laminated film 三亚普罗股份有限公司 2023-04-25 CN disclosed
US-11542397-B2 Liquid composition, quantum dot-containing film, optical film, light-emitting display element panel, and light-emitting display device TOKYO OHKA KOGYO CO., LTD. (JP) 2023-01-03 US disclosed
US-8278030-B2 Sulfonium salt, photoacid generator, and photocurable composition and cured body thereof SAN-APRO LIMITED (JP) 2012-10-02 US disclosed
EP-2399905-A1 SULFONIUM SALT, PHOTO-ACID GENERATOR, AND PHOTOSENSITIVE RESIN COMPOSITION San-Apro Limited (JP) 2011-12-28 EP disclosed
US-20110300482-A1 SULFONIUM SALT, PHOTO-ACID GENERATOR, AND PHOTOSENSITIVE RESIN COMPOSITION SAN-APRO, LTD (JP) 2011-12-08 US disclosed
US-20110039205-A1 SULFONIUM SALT, PHOTOACID GENERATOR, AND PHOTOCURABLE COMPOSITION AND CURED BODY THEREOF SAN-APRO LIMITED (JP) 2011-02-17 US disclosed
EP-2284165-A1 PHOSPHONIUM SALT, PHOTOACID GENERATOR, PHOTO-CURABLE COMPOSITION, AND CURED PRODUCT OF THE PHOTO-CURABLE COMPOSITION San-Apro Limited (JP) 2011-02-16 EP disclosed
US-7709598-B2 Fluorinated alkyl fluorophoshoric acid salts of onium and transition metal complex SAN-APRO LIMITED (JP) 2010-05-04 US disclosed
US-20090163723-A1 METHOD FOR PRODUCING SULFONIUM FLUORINATED ALKYLFLUOROPHOSPHATE SAN-APRO LIMITED (JP) 2009-06-25 US disclosed
EP-1953139-A1 METHOD FOR PRODUCING FLUORINATED SULFONIUM ALKYLFLUOROPHOSPHATE San-Apro Ltd. (JP) 2008-08-06 EP disclosed
US-20070225458-A1 Novel Fluorinated Alkyl Fluorophosphoric Acid Salts of Onium and Ttransition Metal Complex SAN-APRO LIMITED (JP) 2007-09-27 US disclosed
EP-1752463-A1 NOVEL FLUORINATED ALKYLFLUOROPHOSPHORIC ACID SALT OF ONIUM AND TRANSITION METAL COMPLEX San-Apro Limited (JP) 2007-02-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090163723-A1 METHOD FOR PRODUCING SULFONIUM FLUORINATED ALKYLFLUOROPHOSPHATE ARSA, SCO2, DOHH ALDH1A1 1481/4885SMN1; SMN2 2307/4885NPC1 701/4885
US-20110039205-A1 SULFONIUM SALT, PHOTOACID GENERATOR, AND PHOTOCURABLE COMPOSITION AND CURED BODY THEREOF ARSA, ASIC1, TST ALDH1A1 1574/4885SMN1; SMN2 1788/4885NPC1 4053/4885
US-20070225458-A1 Novel Fluorinated Alkyl Fluorophosphoric Acid Salts of Onium and Ttransition Metal Complex AS3MT, TTR, PFAS ALDH1A1 3745/4885SMN1; SMN2 297/4885NPC1 4337/4885
US-20110300482-A1 SULFONIUM SALT, PHOTO-ACID GENERATOR, AND PHOTOSENSITIVE RESIN COMPOSITION ASIC1, H1-0, IK ALDH1A1 2140/4885SMN1; SMN2 2221/4885NPC1 3382/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.