SCHEMBL11289404

SCHEMBL11289404

CC1(C)CN(c2ccccc2I)NC1=O

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.35
GAA P10253 2/20 0.35
MAPT P10636 2/20 0.35
ALDH1A1 P00352 1/20 0.35
G6PD P11413 1/20 0.35
RECQL P46063 1/20 0.35
ALOX5 P09917 4/20 0.34
NOTUM Q6P988 1/20 0.34
RAB9A P51151 1/20 0.33
CNR2 P34972 1/20 0.31
HTR3E A5X5Y0 1/20 0.31
HTR3B O95264 1/20 0.31
HTR3A P46098 1/20 0.31
HTR3D Q70Z44 1/20 0.31
HTR3C Q8WXA8 1/20 0.31
DDB1 Q16531 1/20 0.30
CRBN Q96SW2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8735393 0.82 ALOX5 (0.53) MGLLSMN1; SMN2GAAMAPTALDH1A1
SCHEMBL8904250 0.81 GAA (0.39) SMN1; SMN2GAAMAPTALDH1A1G6PD
SCHEMBL10581683 0.81 ADRA2C (0.38) SMN1; SMN2GAAMAPTALDH1A1G6PD
SCHEMBL11871019 0.78 MGLL (0.42) MGLLSMN1; SMN2GAAMAPTALDH1A1
SCHEMBL8729641 0.76 ADRB1 (0.41) MAPTALDH1A1RECQLALOX5DDB1
SCHEMBL271530 0.76 G6PD (0.55) SMN1; SMN2GAAMAPTALDH1A1G6PD
SCHEMBL11871012 0.71 SMN1; SMN2 (0.47) MGLLSMN1; SMN2GAAMAPTALDH1A1
SCHEMBL10606041 0.70 MEN1 (0.36) SMN1; SMN2MAPTALDH1A1RAB9A
SCHEMBL10606044 0.70 MAPT (0.37) SMN1; SMN2GAAMAPTALDH1A1G6PD
SCHEMBL8729644 0.70 NPSR1 (0.42) SMN1; SMN2GAAMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0064783-A1 Photographic silver halide material for use in the silver complex diffusion transfer reversal process AGFA-GEVAERT N.V. (BE) 1982-11-17 EP disclosed