Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4868570 | 0.85 | ALDH1A1 (0.42) | ALDH1A1NPSR1GAATDP1POLB | |
| SCHEMBL24862 | 0.85 | ALDH1A1 (0.42) | ALDH1A1NPSR1GAATDP1POLB | |
| Glycerin SCHEMBL6129728 | 0.76 | ALDH1A1 (0.43) | ALDH1A1GAAPOLBLMNAKDM4E | |
| Phenol SCHEMBL15518162 | 0.73 | ESR1 (0.41) | ALDH1A1NPSR1TDP1POLBLMNA | |
| Phenol SCHEMBL21963466 | 0.73 | ESR1 (0.41) | ALDH1A1NPSR1TDP1POLBLMNA | |
| Phenol SCHEMBL7159260 | 0.73 | ESR1 (0.41) | ALDH1A1NPSR1TDP1POLBLMNA | |
| SCHEMBL20490158 | 0.71 | ALDH1A1 (0.33) | ALDH1A1NPSR1TDP1 | |
| SCHEMBL9720079 | 0.70 | ALDH1A1 (0.34) | ALDH1A1GAATDP1 | |
| SCHEMBL14370534 | 0.70 | CRBN (0.34) | ALDH1A1LMNA | |
| SCHEMBL1128735 | 0.67 | MAPT (0.37) | ALDH1A1POLBKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 431 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240058259-A1 | COMPOSITIONS COMPRISING ESSENTIAL OILS | FIRMENICH SA (CH) | 2024-02-22 | — | — | US | claimed |
| US-20240000746-A1 | New Cooling Agents and Preparations Containing Them | SYMRISE AG (DE) | 2024-01-04 | — | — | US | claimed |
| EP-4247791-A2 | NEW COOLANTS, AND PREPARATIONS CONTAINING SAME | Symrise AG (DE) | 2023-09-27 | — | — | EP | claimed |
| WO-2023144326-A1 | NEW COOLANTS, AND PREPARATIONS CONTAINING SAME | SYMRISE AG (DE) | 2023-08-03 | — | — | WO | claimed |
| WO-2023143741-A1 | NEW COOLANTS, AND PREPARATIONS CONTAINING SAME | SYMRISE AG (DE) | 2023-08-03 | — | — | WO | claimed |
| WO-2023117119-A1 | ACTIVE INGREDIENTS WITH SIALAGOGUE AND TINGLING/FIZZY EFFECT, AND PREPARATIONS CONTAINING SAME | SYMRISE AG (DE) | 2023-06-29 | — | — | WO | claimed |
| US-20210045983-A1 | RETINOL REPLACEMENT IN SKIN TREATMENT | SYMRISE AG (DE) | 2021-02-18 | — | — | US | claimed |
| EP-3773445-A1 | RETINOL REPLACEMENT IN SKIN TREATMENT | Symrise AG (DE) | 2021-02-17 | — | — | EP | claimed |
| US-20200188289-A1 | COMPOSITIONS COMPRISING ESSENTIAL OILS | FIRMENICH SA (CH) | 2020-06-18 | — | — | US | claimed |
| EP-3624757-A1 | COMPOSITIONS COMPRISING ESSENTIAL OILS | Firmenich SA (CH) | 2020-03-25 | — | — | EP | claimed |
| EP-2416766-A2 | COMPOSITIONS COMPRISING TRANS-TERT-BUTYL CYCLOHEXANOL AS SKIN IRRITATION-REDUCING AGENT | Symrise AG (DE) | 2012-02-15 | — | — | EP | claimed |
| US-20090226537-A1 | MIXTURES COMPRISING ANTHRANILIC ACID AMIDES AND ANTIDANDRUFF AGENTS AS COSMETIC AND PHARMACEUTICAL COMPOSITIONS FOR ALLEVIATING ITCHING | SYMRISE GMBH & CO. KG (DE) | 2009-09-10 | — | — | US | claimed |
| WO-2009087242-A2 | COMPOSITIONS COMPRISING TRANS-TERT-BUTYL CYCLOHEXANOL AS SKIN IRRITATION-REDUCING AGENT | SYMRISE GMBH & CO. KG (DE) | 2009-07-16 | — | — | WO | claimed |
| EP-1959915-A1 | MIXTURES COMPRISING ANTHRANILIC ACID AMIDES AND ANTIDANDRUFF AGENTS AS COSMETIC AND PHARMACEUTICAL COMPOSITIONS FOR ALLEVIATING ITCHING | Symrise GmbH & Co. KG (DE) | 2008-08-27 | — | — | EP | claimed |
| WO-2007062957-A1 | MIXTURES COMPRISING ANTHRANILIC ACID AMIDES AND ANTIDANDRUFF AGENTS AS COSMETIC AND PHARMACEUTICAL COMPOSITIONS FOR ALLEVIATING ITCHING | SYMRISE GMBH & CO. KG (DE) | 2007-06-07 | — | — | WO | claimed |
| EP-0641187-B1 | COOLANT COMPOSITIONS | PROCTER & GAMBLE (US) | 1997-09-17 | — | — | EP | claimed |
| US-5451404-A | Ketals which affect mucous membranes, foods, toiletries, beverages | THE PROCTER & GAMBLE COMPANY (US) | 1995-09-19 | — | — | US | claimed |
| EP-0507190-B1 | Compositions with physiological cooling effect and active compounds suitable for such compositions | HAARMANN & REIMER GMBH (DE) | 1995-06-21 | — | — | EP | claimed |
| EP-0641187-A1 | COOLANT COMPOSITIONS. | PROCTER & GAMBLE (US) | 1995-03-08 | — | — | EP | claimed |
| WO-1993023005-A1 | COOLANT COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1993-11-25 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210045983-A1 | RETINOL REPLACEMENT IN SKIN TREATMENT | RBP1, RBP4, LRAT | ALDH1A1 23/4885NPSR1 2017/4885GAA 1493/4885 |
| US-20240000746-A1 | New Cooling Agents and Preparations Containing Them | TTPA, TREH, TAS2R45 | ALDH1A1 1658/4885NPSR1 2281/4885GAA 2325/4885 |
| US-20090226537-A1 | MIXTURES COMPRISING ANTHRANILIC ACID AMIDES AND ANTIDANDRUFF AGENTS AS COSMETIC AND PHARMACEUTICAL COMPOSITIONS FOR ALLEVIATING ITCHING | H1-0, ASIC1, NHERF1 | ALDH1A1 578/4885NPSR1 503/4885GAA 2106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.