Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 2/20 | 0.52 |
| ▸ | CES1 | P23141 | 2/20 | 0.52 |
| ▸ | MGLL | Q99685 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.49 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.49 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.49 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29779621 | 1.00 | NR4A1 (0.65) | NR4A1ALDH1A1ALOX15CES2CES1 | |
| SCHEMBL9421742 | 0.98 | NR4A1 (0.62) | NR4A1ALDH1A1ALOX15CES2CES1 | |
| SCHEMBL10759830 | 0.90 | CES2 (0.62) | NR4A1ALDH1A1ALOX15CES2CES1 | |
| SCHEMBL3444656 | 0.86 | NR4A1 (0.84) | NR4A1ALDH1A1ALOX15CES2CES1 | |
| SCHEMBL9421738 | 0.85 | ALDH1A1 (0.64) | NR4A1ALDH1A1ALOX15CES2CES1 | |
| SCHEMBL9495711 | 0.85 | NR4A1 (0.70) | NR4A1ALDH1A1CES2CES1SRD5A2 | |
| SCHEMBL29377967 | 0.84 | CES2 (0.56) | ALDH1A1ALOX15CES2CES1SMN1; SMN2 | |
| SCHEMBL896769 | 0.84 | CES2 (0.56) | ALDH1A1ALOX15CES2CES1SMN1; SMN2 | |
| SCHEMBL9507199 | 0.84 | CDC25B (0.60) | NR4A1ALDH1A1ALOX15CES2CES1 | |
| SCHEMBL11116591 | 0.84 | ALB (0.55) | NR4A1ALDH1A1MGLLSMN1; SMN2SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106167548-B | High-performance polysulfone resin and its synthesis | 佛山市珀力玛高新材料有限公司 | 2018-05-01 | — | — | CN | claimed |
| CN-103642029-A | High-fluidity polyethersulfoneketone resin and industrial synthesis method thereof | JIANGMEN YOUJU NEW MATERIALS CO LTD | 2014-03-19 | — | — | CN | claimed |
| CN-103642031-A | High-fluidity polyphenylenesulfoneketone resin and industrial production technology thereof | JIANGMEN YOUJU NEW MATERIALS CO LTD | 2014-03-19 | — | — | CN | claimed |
| CN-103626991-A | High-liquidity poly(ether sulfone ketone) (PESK) resin and industrial production process thereof | JIANGMEN YOUJU NEW MATERIALS CO LTD | 2014-03-12 | — | — | CN | claimed |
| EP-3233799-B1 | DOPAMINE D2 RECEPTOR LIGANDS | BROAD INST INC (US) | 2021-05-19 | — | — | EP | disclosed |
| US-10752588-B2 | Dopamine D2 receptor ligands | THE BROAD INSTITUTE, INC. (US) | 2020-08-25 | — | — | US | disclosed |
| US-20190345105-A9 | DOPAMINE D2 RECEPTOR LIGANDS | THE BROAD INSTITUTE, INC. (US) | 2019-11-14 | — | — | US | disclosed |
| US-20190023656-A1 | DOPAMINE D2 RECEPTOR LIGANDS | THE BROAD INSTITUTE, INC. (US) | 2019-01-24 | — | — | US | disclosed |
| CN-104870519-B | The manufacture method of ring type polyphenylene ether ether one compositions and wire polyphenylene ether ether ketone, the manufacture method of polyphenylene ether ether ketone | 东丽株式会社 | 2017-11-24 | — | — | CN | disclosed |
| EP-3233799-A1 | DOPAMINE D2 RECEPTOR LIGANDS | The Broad Institute Inc. (US) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016100823-A1 | DOPAMINE D2 RECEPTOR LIGANDS | THE BROAD INSTITUTE, INC. (US) | 2016-06-23 | — | — | WO | disclosed |
| CN-103642031-A | High-fluidity polyphenylenesulfoneketone resin and industrial production technology thereof | JIANGMEN YOUJU NEW MATERIALS CO LTD | 2014-03-19 | — | — | CN | disclosed |
| WO-2009143051-A1 | SUBSTITUTED IMIDAZOPYR-AND IMIDAZOTRI-AZINES | OSI PHARMACEUTICALS, INC. (US) | 2009-11-26 | — | — | WO | disclosed |
| US-20090286768-A1 | SUBSTITUTED IMIDAZOPYR- AND IMIDAZOTRI-AZINES | OSI PHARMACEUTICALS, INC. (US) | 2009-11-19 | — | — | US | disclosed |
| CN-101250132-A | Polyfluoro ortho-hydroxybenzamide derivatives and uses thereof | UNIV ZHEJIANG TECHNOLOGY (CN) | 2008-08-27 | — | — | CN | disclosed |
| EP-1630187-B1 | Sulfonic group-containing polyarylene block copolymer, process for production thereof, solid polymer electrolyte and proton conductive membrane | JSR CORP (JP) | 2008-05-21 | — | — | EP | disclosed |
| US-7368068-B2 | Sulfonic group-containing polyarylene block copolymer, process for production thereof, solid polymer electrolyte and proton conductive membrane | JSR CORPORATION (JP) | 2008-05-06 | — | — | US | disclosed |
| US-20060280991-A1 | Membrane-electrode assembly for solid polymer electrolyte fuel cell | HONDA MOTOR CO., LTD. | 2006-12-14 | — | — | US | disclosed |
| US-20060043344-A1 | Sulfonic group-containing polyarylene block copolymer, process for production thereof, solid polymer electrolyte and proton conductive membrane | JSR CORPORATION (JP) | 2006-03-02 | — | — | US | disclosed |
| EP-1630187-A1 | Sulfonic group-containing polyarylene block copolymer, process for production thereof, solid polymer electrolyte and proton conductive membrane | JSR Corporation (JP) | 2006-03-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190345105-A9 | DOPAMINE D2 RECEPTOR LIGANDS | DRD2, SLC6A3, NTSR2 | NR4A1 1089/4885ALDH1A1 1919/4885ALOX15 2824/4885 |
| US-20190023656-A1 | DOPAMINE D2 RECEPTOR LIGANDS | DRD2, SLC6A3, NTSR2 | NR4A1 1089/4885ALDH1A1 1919/4885ALOX15 2824/4885 |
| US-20090286768-A1 | SUBSTITUTED IMIDAZOPYR- AND IMIDAZOTRI-AZINES | ABL1, TPMT, CYP2C19 | NR4A1 312/4885ALDH1A1 292/4885ALOX15 4597/4885 |
| US-10752588-B2 | Dopamine D2 receptor ligands | DRD2, SLC6A3, NTSR2 | NR4A1 1089/4885ALDH1A1 1919/4885ALOX15 2824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.