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SCHEMBL1130779

SCHEMBL1130779

C=C(C)C(=O)SCCSCc1ccc(CSCCSC(=O)C(=C)C)cc1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ CYP2C19 P33261 2/20 0.41
▸ ALDH1A1 P00352 6/20 0.40
▸ LMNA P02545 4/20 0.37
▸ KMT2A Q03164 2/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ SMN1; SMN2 Q16637 3/20 0.35
▸ HPGD P15428 3/20 0.35
▸ RECQL P46063 1/20 0.35
▸ POLB P06746 2/20 0.34
▸ PKM P14618 1/20 0.34
▸ GAA P10253 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ CYP1A2 P05177 1/20 0.33
▸ CYP3A4 P08684 1/20 0.33
▸ CYP2D6 P10635 1/20 0.33
▸ CYP2C9 P11712 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4860565 0.92 CYP2C19 (0.53) CYP2C19ALDH1A1LMNAKMT2ASMN1; SMN2
SCHEMBL1803553 0.87 CYP2C19 (0.40) CYP2C19ALDH1A1LMNAKMT2AMEN1
SCHEMBL1803066 0.83 ALDH1A1 (0.38) CYP2C19ALDH1A1LMNAKMT2AMEN1
SCHEMBL713087 0.83 NOS1 (0.41) KMT2AGAA
SCHEMBL997337 0.80 TSHR (0.36) CYP2C19LMNAKMT2A
SCHEMBL2208055 0.80 TSHR (0.36) CYP2C19LMNAKMT2A
SCHEMBL160486 0.80 TSHR (0.36) CYP2C19LMNAKMT2A
SCHEMBL714832 0.78 TDP1 (0.38) CYP2C19ALDH1A1POLB
SCHEMBL1804131 0.77 TDP1 (0.31) —
SCHEMBL8985546 0.75 CES2 (0.32) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114929455-B Inkjet method for producing spectacle lenses 卡尔蔡司光学国际有限公司 2024-06-14 — — CN disclosed
EP-4065341-B1 INKJET METHOD FOR PRODUCING A SPECTACLE LENS ZEISS CARL VISION INT GMBH (DE) 2023-11-29 — — EP disclosed
US-11794428-B2 Inkjet method for producing a spectacle lens CARL ZEISS VISION INTERNATIONAL GMBH (DE) 2023-10-24 — — US disclosed
EP-3848179-A1 INKJET METHOD FOR PRODUCING A SPECTACLE LENS Carl Zeiss Vision International GmbH (DE) 2021-07-14 — — EP disclosed
EP-1813639-B1 METAL-CONTAINING COMPOUND AND USE THEREOF MITSUI CHEMICALS INC (JP) 2014-03-12 — — EP disclosed
US-7951968-B2 Metal-containing compound and use thereof MITSUI CHEMICALS, INC. (JP) 2011-05-31 — — US disclosed
EP-1323742-B1 Radiation sensitive refractive index changing composition and refractive index changing method JSR CORP (JP) 2011-02-16 — — EP disclosed
US-20100261866-A1 METAL-CONTAINING COMPOUND AND USE THEREOF MITSUI CHEMICALS, INC. (JP) 2010-10-14 — — US disclosed
US-7772348-B2 optical resin, transparent, plastic lenses, high refractive index, heat resistance, strength; polythioether-polyene polymers; resin obtained by polymerization of metal-thiol compound; polythiourethanes, polythioether reacted with triallyl isocyanurate MITSUI CHEMICALS, INC. (JP) 2010-08-10 — — US disclosed
US-7338984-B2 Resin composition containing ultrafine inorganic particle MITSUI CHEMICALS, INC. (JP) 2008-03-04 — — US disclosed
US-6787289-B2 OPTICS JSR CORPORATION (JP) 2004-09-07 — — US disclosed
US-6770735-B2 ORGANIC SULFIDES SUCH AS 1,1,3,3-TETRAKIS(MERCAPTOMETHYLTHIO) PROPANE, USED TO FORM RESINS HAVING HIGH REFRACTIVE INDEX, IMPACT STRENGTH AND HEAT REISTANCE, FOR USE AS LENSES, PRISMS OR OPTICAL FIBER AND FILTERS MITSUI CHEMICALS, INC. (JP) 2004-08-03 — — US disclosed
US-6770734-B2 POLYMERIZABLE TO MAKE POLYTHIOURETHANES; LENSES WITH A HIGH REFRACTIVE INDEX MITSUI CHEMICALS, INC. (JP) 2004-08-03 — — US disclosed
US-20030199668-A1 Process for preparing a thiol compound MITSUI CHEMICALS, INC. (JP) 2003-10-23 — — US disclosed
US-20030149230-A1 Polythiol compound MITSUI CHEMICALS, INC. (JP) 2003-08-07 — — US disclosed
US-20030139486-A1 Radiation sensitive refractive index changing composition and refractive index changing method JSR CORPORATION (JP) 2003-07-24 — — US disclosed
US-6596841-B2 For producing resin which is used for optical material such as a plastic lens, a prism, an optical fiber, a substrate for an information recording medium, a filter and a light emitting diodes; refractive index MITSUI CHEMICALS, INC. (JP) 2003-07-22 — — US disclosed
EP-1323742-A2 Radiation sensitive refractive index changing composition and refractive index changing method JSR Corporation (JP) 2003-07-02 — — EP disclosed
US-20020022713-A1 Polythiol, polymerizable composition, resin and lens, and process for preparing thiol compound MITSUI CHEMICALS, INC. (JP) 2002-02-21 — — US disclosed
EP-1138670-A1 Polythiol, polymerizable composition, resin and lens, and process for preparing thiol compound Mitsui Chemicals, Inc. (JP) 2001-10-04 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100261866-A1 METAL-CONTAINING COMPOUND AND USE THEREOF HSPH1, HSPA4L, PTCD3 CYP2C19 3397/4885ALDH1A1 2543/4885LMNA 3244/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.