Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 14/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL331133 | 0.90 | IDO1 (0.47) | NOS1IDO1NOS3NOS2TDP1 | |
| SCHEMBL26192578 | 0.89 | ACACB (0.38) | KMT2A | |
| SCHEMBL27472188 | 0.87 | NOS1 (0.31) | NOS1IDO1NOS3NOS2TDP1 | |
| SCHEMBL1801901 | 0.84 | SLC11A2 (0.47) | NOS1IDO1NOS3NOS2TDP1 | |
| SCHEMBL1130779 | 0.83 | CYP2C19 (0.41) | KMT2AGAA | |
| SCHEMBL12990577 | 0.80 | TDP1 (0.39) | TDP1L3MBTL1KMT2ATAAR1 | |
| SCHEMBL1802036 | 0.79 | ALDH1A1 (0.35) | IDO1TDP1L3MBTL1GAATAAR1 | |
| SCHEMBL26192576 | 0.75 | SLC11A2 (0.36) | NOS1IDO1L3MBTL1TAAR1 | |
| SCHEMBL4860565 | 0.75 | CYP2C19 (0.53) | IDO1KMT2A | |
| SCHEMBL11564332 | 0.74 | ALDH1A1 (0.44) | TDP1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 233 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022496-A | Chromene compound | TOKUYAMA CORPORATION (JP) | 2000-02-08 | — | — | US | claimed |
| EP-0745620-A1 | Polymerisable compositions based on thio(meth)acrylate monomers, polymers having low yellowness index made from these compositions and ophthalmic lenses made therefrom | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 1996-12-04 | — | — | EP | claimed |
| US-12624048-B2 | Photochromic cyclic compound and curable composition containing the photochromic cyclic compound | TOKUYAMA CORPORATION (JP) | 2026-05-12 | — | — | US | disclosed |
| US-12595408-B2 | Photochromic compound, naphthol derivative, curable composition, optical article, lens, and eyeglasses | TOKUYAMA CORPORATION (JP) | 2026-04-07 | — | — | US | disclosed |
| US-12570894-B2 | Photochromic compound and curable composition containing the photochromic compound | TOKUYAMA CORPORATION (JP) | 2026-03-10 | — | — | US | disclosed |
| EP-4692072-A1 | PHOTOCHROMIC COMPOUND, PROPARGYL ALCOHOL COMPOUND, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND SPECTACLES | TOKUYAMA CORPORATION (JP) | 2026-02-11 | — | — | EP | disclosed |
| EP-4692071-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASS | TOKUYAMA CORPORATION (JP) | 2026-02-11 | — | — | EP | disclosed |
| EP-3779572-B1 | OPTICAL ARTICLE | HOYA LENS THAILAND LTD (TH) | 2025-11-19 | — | — | EP | disclosed |
| US-20250122163-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | TOKUYAMA CORPORATION (JP) | 2025-04-17 | — | — | US | disclosed |
| WO-2025070122-A1 | PHOTOCHROMIC COMPOSITION, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | 株式会社トクヤマ | 2025-04-03 | — | — | WO | disclosed |
| US-20250101294-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | TOKUYAMA CORPORATION (JP) | 2025-03-27 | — | — | US | disclosed |
| US-5631382-A | PHOTOCHROMIC LENSES | TOKUYAMA CORPORATION (JP) | 1997-05-20 | — | — | US | disclosed |
| EP-0745620-A1 | Polymerisable compositions based on thio(meth)acrylate monomers, polymers having low yellowness index made from these compositions and ophthalmic lenses made therefrom | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 1996-12-04 | — | — | EP | disclosed |
| EP-0273710-B2 | Resin having high refractive index, process for producing said resin and optical materials composed of said resin | NIPPON CATALYTIC CHEM IND (JP) | 1996-10-16 | — | — | EP | disclosed |
| EP-0696582-A1 | Polycyclic spirophthalimide derivatives, process for their preparation and their use as fulgimides | TOKUYAMA CORPORATION (JP) | 1996-02-14 | — | — | EP | disclosed |
| EP-0629626-A2 | Cyclopropyl-substituted spiro-photochromic compounds | TOKUYAMA CORPORATION (JP) | 1994-12-21 | — | — | EP | disclosed |
| EP-0629656-A2 | Photochromic article | NIKON CORPORATION (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5246989-A | PHOTOCHROMIC COMPOUND, COMPOSITION AND USE THEREOF | TOKUYAMA SODA KABISHIKI KAISHA (JP) | 1993-09-21 | — | — | US | disclosed |
| EP-0449669-A1 | Photochromic compound, composition and use thereof | TOKUYAMA CORPORATION (JP) | 1991-10-02 | — | — | EP | disclosed |
| EP-0273710-A2 | Resin having high refractive index, process for producing said resin and optical materials composed of said resin | Nippon Shokubai Kagaku Kogyo Co., Ltd (JP) | 1988-07-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12595408-B2 | Photochromic compound, naphthol derivative, curable composition, optical article, lens, and eyeglasses | CRYAA, CRYZ, CRY2 | NOS1 1546/4885IDO1 1204/4885NOS3 1924/4885 |
| US-20250122163-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | CCNE1, NAP1L1, CRYZ | NOS1 712/4885IDO1 1481/4885NOS3 1437/4885 |
| US-12570894-B2 | Photochromic compound and curable composition containing the photochromic compound | SMC4, HBG2, SPTBN1 | NOS1 1043/4885IDO1 1797/4885NOS3 505/4885 |
| US-20250101294-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | NAP1L1, CRYAA, CRYZ | NOS1 1269/4885IDO1 779/4885NOS3 2438/4885 |
| US-12624048-B2 | Photochromic cyclic compound and curable composition containing the photochromic cyclic compound | CCNL2, CRY2, CRY1 | NOS1 1726/4885IDO1 2694/4885NOS3 2174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.