SCHEMBL11318079

SCHEMBL11318079

C/C=C/CONc1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.34
NPSR1 Q6W5P4 1/20 0.32
ALDH1A1 P00352 5/20 0.32
TDP1 Q9NUW8 3/20 0.32
HSD17B10 Q99714 3/20 0.32
CTSD P07339 1/20 0.32
MAPT P10636 1/20 0.31
SOAT2 O75908 1/20 0.31
SOAT1 P35610 1/20 0.31
ALOX15 P16050 2/20 0.31
ALOX12 P18054 2/20 0.31
MAPK1 P28482 2/20 0.31
PTGS1 P23219 1/20 0.31
SLC6A2 P23975 1/20 0.31
PTGS2 P35354 1/20 0.31
HTR2B P41595 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CYP3A4 P08684 1/20 0.31
HIF1A Q16665 1/20 0.31
ALOX5 P09917 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9090785 1.00 TSHR (0.34) TSHRNPSR1ALDH1A1TDP1HSD17B10
Oxalic Acid SCHEMBL9722961 0.91 ALOX5 (0.37) TSHRALDH1A1TDP1HSD17B10MAPT
SCHEMBL12374749 0.81 CTSD (0.37) ALDH1A1CTSD
SCHEMBL942986 0.75 ALDH1A1 (0.43) TSHRNPSR1ALDH1A1TDP1HSD17B10
SCHEMBL587239 0.75 HSD17B10 (0.40) TSHRALDH1A1TDP1HSD17B10CTSD
SCHEMBL11510562 0.74 MAPT (0.37) TSHRALDH1A1HSD17B10MAPTCYP3A4
SCHEMBL10490491 0.74 SOAT2 (0.54) TSHRALDH1A1TDP1HSD17B10SOAT2
SCHEMBL45188 0.72 KCNH3 (0.49) TSHRNPSR1ALDH1A1TDP1HSD17B10
SCHEMBL28187507 0.71 HTT (0.38) TSHRALDH1A1TDP1HSD17B10CTSD
Hydrochloric Acid SCHEMBL28313389 0.70 KCNH3 (0.51) TSHRNPSR1ALDH1A1TDP1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4255183-A HERBICIDES HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) 1981-03-10 US disclosed