Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.30 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11510563 | 0.76 | MAPT (0.40) | MAPTTAS2R38NAPRTHSD17B10GAA | |
| SCHEMBL11511465 | 0.74 | RAB9A (0.48) | MAPTNAPRTHSD17B10HPGDTSHR | |
| SCHEMBL9090785 | 0.74 | TSHR (0.34) | MAPTHSD17B10HPGDTSHRCYP3A4 | |
| SCHEMBL11318079 | 0.74 | TSHR (0.34) | MAPTHSD17B10HPGDTSHRCYP3A4 | |
| Oxalic Acid SCHEMBL9722961 | 0.71 | ALOX5 (0.37) | MAPTNAPRTHSD17B10GAAHPGD | |
| SCHEMBL9322402 | 0.67 | GPR174 (0.49) | MAPTTAS2R38NAPRTHSD17B10GAA | |
| SCHEMBL941357 | 0.67 | NAPRT (0.47) | MAPTNAPRTHSD17B10GAAHPGD | |
| SCHEMBL45188 | 0.66 | KCNH3 (0.49) | MAPTHSD17B10GAAHPGDTSHR | |
| SCHEMBL11313866 | 0.66 | IDO1 (0.42) | MAPTTAS2R38NAPRTHSD17B10GAA | |
| SCHEMBL587239 | 0.66 | HSD17B10 (0.40) | MAPTHSD17B10TSHRCYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147711-A | Ethylenic silicon compounds and thermoplastic elastomers obtained therefrom | RHONE-POULENC INDUSTRIES (FR) | 1979-04-03 | — | — | US | claimed |