Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | ADAM9 | Q13443 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2893907 | 0.75 | SMN1; SMN2 (0.52) | SMN1; SMN2NPSR1ALDH1A1DAOADAM17 | |
| SCHEMBL7097777 | 0.74 | ALDH1A1 (0.60) | SMN1; SMN2NPSR1ALDH1A1ADAM17MMP2 | |
| SCHEMBL15972776 | 0.74 | ALDH1A1 (0.60) | SMN1; SMN2NPSR1ALDH1A1ADAM17MMP2 | |
| SCHEMBL542982 | 0.70 | KMT2A (0.49) | — | |
| SCHEMBL1108471 | 0.67 | ALDH1A1 (0.52) | SMN1; SMN2NPSR1ALDH1A1ADAM17MMP2 | |
| SCHEMBL14945759 | 0.67 | SMN1; SMN2 (0.50) | SMN1; SMN2NPSR1ALDH1A1TAAR1MMP2 | |
| SCHEMBL17939 | 0.66 | IDO1 (0.59) | NPSR1ALDH1A1HTTIDO1MTNR1A | |
| SCHEMBL8105572 | 0.66 | IDO1 (0.42) | ALDH1A1HTTDAOIDO1TAAR1 | |
| SCHEMBL2673236 | 0.66 | MAPT (0.50) | ALDH1A1IDO1TAAR1CHRM2CHRM1 | |
| SCHEMBL1358880 | 0.65 | SMN1; SMN2 (0.47) | SMN1; SMN2NPSR1ALDH1A1ADAM17MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993800-B2 | Process for producing optically active α-methylcysteine derivative | KANEKA CORPORATION (JP) | 2015-03-31 | — | — | US | disclosed |
| EP-2287152-B1 | Process for producing optically active alpha-methylcysteine derivative | KANEKA CORP (JP) | 2015-01-14 | — | — | EP | disclosed |
| US-20130261331-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ALPHA-METHYLCYSTEINE DERIVATIVE | KANEKA CORP (JP) | 2013-10-03 | — | — | US | disclosed |
| EP-2287152-A2 | Process for producing optically active alpha-methylcysteine derivative | KANEKA CORPORATION (JP) | 2011-02-23 | — | — | EP | disclosed |
| US-20100197934-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ALPHA-METHYLCYSTEINE DERIVATIVE | KANEKA CORPORATION (JP) | 2010-08-05 | — | — | US | disclosed |
| US-20060105435-A1 | Process for producing optically active alpha-methylcysteine derivative | KANEKA CORPORATION (JP) | 2006-05-18 | — | — | US | disclosed |
| EP-1550725-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE alpha-METHYLCYSTEINE DERIVATIVE | KANEKA CORPORATION (JP) | 2005-07-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197934-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ALPHA-METHYLCYSTEINE DERIVATIVE | AHCY, CTH, BHMT | SMN1; SMN2 4472/4885NPSR1 3262/4885ALDH1A1 930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.