Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 3/20 | 0.63 |
| ▸ | CYCS | P99999 | 4/20 | 0.57 |
| ▸ | STAT3 | P40763 | 1/20 | 0.55 |
| ▸ | STAT1 | P42224 | 1/20 | 0.55 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22332272 | 0.91 | TOP1 (0.70) | TOP1CYCSSTAT3STAT1ABCG2 | |
| SCHEMBL11339474 | 0.89 | TOP1 (0.75) | TOP1CYCSSTAT3STAT1ABCG2 | |
| SCHEMBL140681 | 0.89 | TOP1 (0.67) | TOP1CYCSSTAT3STAT1ABCG2 | |
| SCHEMBL11334086 | 0.88 | TOP1 (0.65) | TOP1CYCSSTAT3STAT1ABCG2 | |
| SCHEMBL28919688 | 0.88 | TOP1 (0.65) | TOP1CYCSSTAT3STAT1ABCG2 | |
| SCHEMBL17894094 | 0.84 | TOP1 (0.75) | TOP1CYCSSTAT3STAT1ABCG2 | |
| SCHEMBL26285347 | 0.84 | TOP1 (0.57) | TOP1CYCSSTAT3STAT1ABCG2 | |
| SCHEMBL14246834 | 0.81 | CYCS (0.62) | TOP1CYCSSTAT3STAT1ABCG2 | |
| SCHEMBL29664855 | 0.81 | CYCS (0.62) | TOP1CYCSSTAT3STAT1ABCG2 | |
| SCHEMBL13547831 | 0.80 | STAT3 (0.56) | TOP1CYCSSTAT3STAT1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105936638-A | Porphyrin compound and preparation method and application thereof in surface enhanced Raman probe | 辽宁大学 | 2016-09-14 | — | — | CN | disclosed |