SCHEMBL14246834

SCHEMBL14246834

O=C(O)c1cc(C(=O)O)cc(-c2c3nc(cc4ccc([nH]4)c(-c4cc(C(=O)O)cc(C(=O)O)c4)c4nc(cc5ccc2[nH]5)C=C4)C=C3)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYCS P99999 4/20 0.62
▸ STAT3 P40763 1/20 0.61
▸ STAT1 P42224 1/20 0.61
▸ TOP1 P11387 3/20 0.55
▸ ENPP2 Q13822 1/20 0.37
▸ KDM4E B2RXH2 1/20 0.36
▸ NPC1 O15118 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ HPGD P15428 1/20 0.36
▸ RAB9A P51151 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ ABCG2 Q9UNQ0 1/20 0.36
▸ TERT O14746 2/20 0.34
▸ CASP3 P42574 1/20 0.33
▸ SENP8 Q96LD8 1/20 0.33
▸ SENP7 Q9BQF6 1/20 0.33
▸ SENP6 Q9GZR1 1/20 0.33
▸ NR4A2 P43354 1/20 0.33
▸ MMP2 P08253 1/20 0.33
▸ MMP9 P14780 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29664855 1.00 CYCS (0.62) CYCSSTAT3STAT1TOP1ENPP2
SCHEMBL22332272 0.90 TOP1 (0.70) CYCSSTAT3STAT1TOP1ENPP2
SCHEMBL140681 0.87 TOP1 (0.67) CYCSSTAT3STAT1TOP1ENPP2
SCHEMBL11339474 0.87 TOP1 (0.75) CYCSSTAT3STAT1TOP1ENPP2
SCHEMBL11334086 0.86 TOP1 (0.65) CYCSSTAT3STAT1TOP1ENPP2
SCHEMBL28919688 0.86 TOP1 (0.65) CYCSSTAT3STAT1TOP1ENPP2
SCHEMBL29684505 0.84 CYCS (0.83) CYCSSTAT3STAT1TOP1ENPP2
SCHEMBL14246889 0.84 CYCS (0.83) CYCSSTAT3STAT1TOP1ENPP2
SCHEMBL29283645 0.84 STAT3 (0.58) CYCSSTAT3STAT1TOP1ENPP2
SCHEMBL17894094 0.82 TOP1 (0.75) CYCSSTAT3STAT1TOP1ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12546743-B2 Electrochemical sensor and related methods UNIVERSITY OF SOUTH FLORIDA (US) 2026-02-10 — — US disclosed
US-20230296554-A1 ELECTROCHEMICAL SENSOR AND RELATED METHODS UNIVERSITY OF SOUTH FLORIDA 2023-09-21 — — US disclosed
US-20160280714-A1 POLYHEDRAL CAGE-CONTAINING METALLOPORPHYRIN FRAMEWORKS, METHODS OF MAKING, AND METHODS OF USING UNIVERSITY OF SOUTH FLORIDA (US) 2016-09-29 — — US disclosed
EP-2721032-A2 POLYHEDRAL CAGE-CONTAINING METALLOPORPHYRIN FRAMEWORKS, METHODS OF MAKING, AND METHODS OF USING University Of South Florida (US) 2014-04-23 — — EP disclosed
US-20140107333-A1 POLYHEDRAL CAGE-CONTAINING METALLOPORPHYRIN FRAMEWORKS, METHODS OF MAKING, AND METHODS OF USING UNIVERSITY OF SOUTH FLORIDA 2014-04-17 — — US disclosed
WO-2012174379-A2 POLYHEDRAL CAGE-CONTAINING METALLOPORPHYRIN FRAMEWORKS, METHODS OF MAKING, AND METHODS OF USING UNIVERSITY OF SOUTH FLORIDA (US) 2012-12-20 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140107333-A1 POLYHEDRAL CAGE-CONTAINING METALLOPORPHYRIN FRAMEWORKS, METHODS OF MAKING, AND METHODS OF USING PCBP1, HNRNPF, YTHDF2 CYCS 371/4885STAT3 3544/4885STAT1 3734/4885
US-12546743-B2 Electrochemical sensor and related methods EPX, MUC1, EPCAM CYCS 2095/4885STAT3 608/4885STAT1 694/4885
US-20160280714-A1 POLYHEDRAL CAGE-CONTAINING METALLOPORPHYRIN FRAMEWORKS, METHODS OF MAKING, AND METHODS OF USING PCBP1, HNRNPF, YTHDF2 CYCS 371/4885STAT3 3544/4885STAT1 3734/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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