SCHEMBL1284428

SCHEMBL1284428

OC(F)(C(F)(F)F)C(F)(F)c1ccc(C(F)(F)C(O)(F)C(F)(F)F)cc1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 1/20 0.40
PGK2 P07205 1/20 0.40
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
NR1H2 P55055 11/20 0.39
NR1H3 Q13133 11/20 0.39
HSD11B1 P28845 1/20 0.35
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35
KIF11 P52732 1/20 0.35
MLYCD O95822 1/20 0.34
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
ORAI1 Q96D31 1/20 0.33
ORAI2 Q96SN7 1/20 0.33
ORAI3 Q9BRQ5 1/20 0.33
TRPV6 Q9H1D0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9621272 0.92 KIF11 (0.46) PGK1PGK2ESR1ESR2NR1H2
SCHEMBL8560690 0.90 USP2 (0.43) PGK1PGK2ESR1ESR2NR1H2
SCHEMBL9508396 0.90 ESR1 (0.56) PGK1PGK2ESR1ESR2ALDH1A1
SCHEMBL1357633 0.89 ALDH1A1 (0.50) PGK1PGK2NR1H2NR1H3HSD11B1
SCHEMBL2776477 0.88 MLYCD (0.50) NR1H2NR1H3TSHRMLYCD
SCHEMBL4982243 0.88 KIF11 (0.46) PGK1PGK2ESR1ESR2NR1H2
SCHEMBL1134055 0.82 ALDH1A1 (0.44) PGK1PGK2ESR1ESR2NR1H2
SCHEMBL6339219 0.82 MEN1 (0.42) NR1H2NR1H3HSD11B1ALDH1A1KIF11
SCHEMBL11410841 0.82 KIF11 (0.52) NR1H2NR1H3ALDH1A1TSHRKIF11
SCHEMBL2465498 0.79 PGK1 (0.48) PGK1PGK2ESR1ESR2NR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-1066133-A None JP disclosed
US-11667808-B2 Hydrophilic coating material, method for producing the same and inkjet recording head CANON KABUSHIKI KAISHA (JP) 2023-06-06 US disclosed
EP-4031597-A1 METHODS OF PRODUCING COATED PROPPANTS Saudi Arabian Oil Company (SA) 2022-07-27 EP disclosed
WO-2021055003-A1 METHODS OF PRODUCING COATED PROPPANTS SAUDI ARABIAN OIL COMPANY (SA) 2021-03-25 WO disclosed
US-20210079293-A1 METHODS OF PRODUCING COATED PROPPANTS SAUDI ARABIAN OIL COMPANY (SA) 2021-03-18 US disclosed
US-20200407589-A1 HYDROPHILIC COATING MATERIAL, METHOD FOR PRODUCING THE SAME AND INKJET RECORDING HEAD CANON KABUSHIKI KAISHA (JP) 2020-12-31 US disclosed
US-10761080-B2 Detecting a marker in a liquid SICPA HOLDING SA (CH) 2020-09-01 US disclosed
EP-3201614-B1 DETECTING A MARKER IN A LIQUID SICPA HOLDING SA (CH) 2020-03-04 EP disclosed
US-20170269056-A1 DETECTING A MARKER IN A LIQUID SICPA HOLDING SA (CH) 2017-09-21 US disclosed
US-8622516-B2 Ink jet recording head and method of producing ink jet recording head CANON KABUSHIKI KAISHA (JP) 2014-01-07 US disclosed
US-20020123608-A1 Fluorinated polymer and coating composition 21ST CENTURY COATINGS (AUST) PTY LTD (AU) 2002-09-05 US disclosed
US-6291545-B2 USABLE FOR TREATING SPECIFIED SURFACE OF A MEMBER OR DEVICE SO AS TO IMPART LIQUID REPELLENT PROPERTY SUCH AS FOR INK JET HEADS; AS ADHESIVE CANON KABUSHIKI KAISHA (JP) 2001-09-18 US disclosed
EP-0837085-A1 POLYCARBONATE-BASE POLYMER, PRODUCTION PROCESS, RESIN COATING FLUID PREPARED THEREFROM, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PREPARED THEREFROM IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-04-22 EP disclosed
US-4990689-A 2,4-bis(2-hydroxyhexafluoro-2-propyl)fluorobenzene and method of preparing same CENTRAL GLASS COMPANY, LIMITED (JP) 1991-02-05 US disclosed
JP-S6466133-A SEPARATION OF 1,4-BIS2(-HYDROXYHEXAFLUORO-2-PROPYL) BENZENE CENTRAL GLASS CO LTD 1989-03-13 JP disclosed
EP-0254219-A1 Process for the separation of mixtures of isomeres from 1,3- and 1,4-bis-(2-hydroxyhexafluoro-2-propyl)-benzene HOECHST AKTIENGESELLSCHAFT (DE) 1988-01-27 EP disclosed
US-4477643-A Fluorinated polyurethanes THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1984-10-16 US disclosed
US-4284747-A Cis-trans fluoropolyol polyacrylate THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1981-08-18 US disclosed
US-4157358-A POLYURETHANE COATINGS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1979-06-05 US disclosed
US-4132681-A Fluorinated polyether network polymers UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1979-01-02 US disclosed