Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.55 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.46 |
| ▸ | FABP3 | P05413 | 1/20 | 0.46 |
| ▸ | FABP4 | P15090 | 1/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890007 | 0.86 | HNF4A (0.66) | HNF4AACMSDMCL1KDM4ELMNA | |
| SCHEMBL19999156 | 0.82 | HPGD (0.57) | KDM4ELMNASMN1; SMN2PDE10AMEN1 | |
| SCHEMBL17164118 | 0.80 | NR4A1 (0.52) | HNF4AACMSDMCL1KDM4ELMNA | |
| SCHEMBL7407371 | 0.76 | HNF4A (0.73) | HNF4ALMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10596069 | 0.75 | GPR35 (0.59) | KDM4ELMNASMN1; SMN2PDE10AMEN1 | |
| SCHEMBL6764706 | 0.75 | DHODH (0.51) | HNF4AACMSDMCL1KDM4ELMNA | |
| SCHEMBL11364286 | 0.75 | GPR35 (0.46) | HNF4AKDM4ELMNASMN1; SMN2PDE10A | |
| SCHEMBL30080985 | 0.75 | METAP2 (0.48) | HNF4AKDM4EMEN1KMT2AHPGD | |
| SCHEMBL28322994 | 0.75 | METAP2 (0.48) | HNF4AKDM4EMEN1KMT2AHPGD | |
| SCHEMBL17177742 | 0.75 | HSD17B10 (0.50) | HNF4AACMSDMCL1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410303-B2 | Direct conversion of phenols into amides and esters of benzoic acid | The Florida State University Research Foundation, Inc. (US) | 2013-04-02 | — | — | US | disclosed |
| US-20110237798-A1 | DIRECT CONVERSION OF PHENOLS INTO AMIDES AND ESTERS OF BENZOIC ACID | The Florida State University Research Foundation, Inc. (US) | 2011-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237798-A1 | DIRECT CONVERSION OF PHENOLS INTO AMIDES AND ESTERS OF BENZOIC ACID | DDC, NISCH, TST | HNF4A 882/4885ACMSD 17/4885MCL1 4171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.