Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KIT | P10721 | 4/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.32 |
| ▸ | FLT4 | P35916 | 4/20 | 0.32 |
| ▸ | KDR | P35968 | 4/20 | 0.32 |
| ▸ | FLT3 | P36888 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 4/20 | 0.32 |
| ▸ | FLT1 | P17948 | 3/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11381322 | 0.74 | ALDH1A1 (0.61) | MEN1KMT2AALDH1A1RAB9ALMNA | |
| SCHEMBL11381891 | 0.73 | CNR1 (0.37) | CYP19A1MEN1KMT2A | |
| SCHEMBL31545431 | 0.73 | CNR2 (0.51) | MEN1KMT2A | |
| SCHEMBL11383677 | 0.71 | PTGS2 (0.35) | CYP19A1MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL11383684 | 0.71 | PTGS2 (0.35) | CYP19A1MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL11380256 | 0.69 | KDR (0.34) | KDR | |
| SCHEMBL11384600 | 0.68 | KDR (0.32) | KDR | |
| SCHEMBL11375232 | 0.67 | RIPK1 (0.31) | — | |
| SCHEMBL11808579 | 0.60 | GRIN2D (0.47) | ALDH1A1PDGFRAPDGFRBTSHRHPGD | |
| SCHEMBL24622738 | 0.58 | CNR2 (0.45) | MEN1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4243674-A | HYPOTENSIVE AGENTS; ANALGESICS; ANTISECRETORY AGENTS; ANTIBODY INHIBITORS, AND TRANQUILIZERS | PFIZER INC. (US) | 1981-01-06 | — | — | US | disclosed |
| US-4143139-A | ANALGESICS, HYPOTENSIVES, IMMUNOSUPPRESSANTS, TRANQUILIZERS, ANTISECRETORY, ANTI-ANXIETY | PFIZER INC. (US) | 1979-03-06 | — | — | US | disclosed |