Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | GUSB | P08236 | 4/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11384755 | 0.89 | PDE5A (0.42) | PKMPDE5AGUSBTNKSCA1 | |
| SCHEMBL11386259 | 0.87 | PDE5A (0.53) | PDE5AKMT2A | |
| SCHEMBL11381526 | 0.86 | NPSR1 (0.50) | PKMGUSBALDH1A1KDM4EHPGD | |
| SCHEMBL11377346 | 0.85 | NPSR1 (0.46) | PDE5AGUSBCYP1A1CYP1B1ALDH1A1 | |
| SCHEMBL11389378 | 0.85 | PDE5A (0.46) | PDE5AALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL11381304 | 0.85 | PDE5A (0.48) | PDE5AALDH1A1KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL11380547 | 0.84 | MGLL (0.48) | GUSBCYP1A1CYP1B1CYP1A2ALDH1A1 | |
| SCHEMBL11375670 | 0.84 | GUSB (0.56) | GUSBKDM4EHPGDPOLBTSHR | |
| SCHEMBL11375402 | 0.83 | AMY1A (0.50) | GUSBCYP1A1CYP1B1TNKSPOLB | |
| SCHEMBL11382413 | 0.82 | GUSB (0.59) | GUSBCYP1A1CYP1B1TNKSCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | claimed |
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | disclosed |