Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28406269 | 0.84 | CA2 (0.49) | MAPK1MAPTTDP1KDM4EMEN1 | |
| SCHEMBL1516246 | 0.82 | MAPK1 (0.58) | MAPK1MAPTTDP1KDM4EMEN1 | |
| SCHEMBL137832 | 0.80 | MAPK1 (0.56) | MAPK1MAPTTDP1KDM4EMEN1 | |
| SCHEMBL27871177 | 0.79 | HSD11B1 (0.35) | MAPK1MAPTTDP1KDM4EMEN1 | |
| SCHEMBL31356885 | 0.79 | HSD11B1 (0.65) | MAPK1MAPTTDP1KDM4EMEN1 | |
| SCHEMBL2188285 | 0.78 | MAPT (0.54) | MAPK1MAPTTDP1KDM4EMEN1 | |
| SCHEMBL260911 | 0.78 | ALDH1A1 (0.56) | MAPK1MAPTTDP1KDM4EMEN1 | |
| SCHEMBL7149069 | 0.78 | MAPK1 (0.54) | MAPK1MAPTTDP1KDM4EMEN1 | |
| SCHEMBL9197870 | 0.78 | MAPK1 (0.54) | MAPK1MAPTTDP1KDM4EMEN1 | |
| SCHEMBL7868384 | 0.78 | MAPK1 (0.54) | MAPK1MAPTTDP1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3975 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12060334-B2 | 3-substituted phenazine derivatives as antimicrobial agents | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-08-13 | — | — | US | claimed |
| EP-3715346-B1 | THIAZOLYL-CONTAINING COMPOUNDS FOR TREATING PROLIFERATIVE DISEASES | DANA FARBER CANCER INST INC (US) | 2024-01-03 | — | — | EP | claimed |
| EP-3606528-B1 | TRICYCLIC COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK3) INHIBITORS AND USES THEREOF | BROAD INST INC (US) | 2023-10-18 | — | — | EP | claimed |
| CN-115128195-A | LC-MS/MS detection method for pesticide and veterinary drug residues in animal oil and vegetable oil | 北京市疾病预防控制中心 | 2022-09-30 | — | — | CN | claimed |
| EP-3291676-B1 | MITRAGYNINE ANALOGS AND USES THEREOF | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2022-08-17 | — | — | EP | claimed |
| CN-111060638-B | Screening and confirming method for 207 veterinary drugs and additives in animal food | 河南省兽药饲料监察所(河南省畜产品质量监测检验中心) | 2022-06-03 | — | — | CN | claimed |
| US-11241435-B2 | Uses of salt-inducible kinase (SIK) inhibitors for treating osteoporosis | THE GENERAL HOSPITAL CORPORATION (US) | 2022-02-08 | — | — | US | claimed |
| EP-3172213-B1 | MACROCYCLIC KINASE INHIBITORS AND USES THEREOF | DANA FARBER CANCER INST INC (US) | 2021-09-22 | — | — | EP | claimed |
| EP-3092220-B1 | VITAMIN C PRODRUGS AND USES THEREOF | UNIV FLORIDA (US) | 2021-01-20 | — | — | EP | claimed |
| US-10870651-B2 | Inhibitors of cyclin-dependent kinase 7 (CDK7) | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-12-22 | — | — | US | claimed |
| CN-107490649-B | Method for screening 62 antibacterial drugs in livestock and poultry excrement | 河南省兽药饲料监察所 | 2020-05-12 | — | — | CN | claimed |
| CN-111060638-A | Screening and confirming method for 207 veterinary drugs and additives in animal food | 河南省兽药饲料监察所(河南省畜产品质量监测检验中心) | 2020-04-24 | — | — | CN | claimed |
| EP-3209648-B1 | THIAZOLYL-CONTAINING COMPOUNDS FOR TREATING PROLIFERATIVE DISEASES | DANA FARBER CANCER INST INC (US) | 2020-03-11 | — | — | EP | claimed |
| US-10112957-B2 | Thiazolyl-containing compounds for treating proliferative diseases | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-10-30 | — | — | US | claimed |
| US-9856225-B2 | Substituted phenazines as antimicrobial agents | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2018-01-02 | — | — | US | claimed |
| EP-2550285-B1 | TRIOXACARCINS AND USES THEREOF | HARVARD COLLEGE (US) | 2017-07-19 | — | — | EP | claimed |
| US-20150376201-A1 | CORTISTATIN ANALOGUES AND SYNTHESES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-12-31 | — | — | US | claimed |
| US-7834184-B2 | Opiate intermediates and methods of synthesis | MALLINCKRODT INC. | 2010-11-16 | — | — | US | claimed |
| EP-1447397-A1 | Polyfunctional sulfonamides and sulfonates and process for preparing them | Ecole Polytechnique Fédérale de Lausanne (CH) | 2004-08-18 | — | — | EP | claimed |
| US-4958018-A | REACTING A 3-HALOMETHYL-3-CEPHEM WITH A LEAD REDUCING AGENT | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1990-09-18 | — | — | US | claimed |