Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | PRKCB | P05771 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11550186 | 0.86 | HSD11B1 (0.50) | HSD11B1TP53CSNK2A1LMNAMAPT | |
| SCHEMBL11434207 | 0.84 | RORB (0.41) | HSD11B1MAPTMAPK14 | |
| SCHEMBL11551693 | 0.82 | CYP2A6 (0.52) | HSD11B1P2RX7GRM2LMNAGAA | |
| SCHEMBL11554969 | 0.82 | BRD4 (0.43) | LMNAMAPTBRD4 | |
| SCHEMBL11440224 | 0.81 | HSD17B10 (0.41) | LMNABRD4 | |
| SCHEMBL11428886 | 0.81 | ALDH1A1 (0.36) | LMNAMAPTBRD4ATM | |
| SCHEMBL11436445 | 0.81 | CHRM3 (0.36) | LMNAMAPTBRD4ATM | |
| SCHEMBL11426220 | 0.79 | BRD4 (0.44) | LMNAMAPTBRD4 | |
| SCHEMBL11441314 | 0.78 | BRD4 (0.52) | LMNAMAPTGAABRD4 | |
| SCHEMBL11429053 | 0.77 | GSK3B (0.42) | HSD11B1LMNAMEN1KMT2ABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152136-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1979-05-01 | — | — | US | disclosed |