Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 2/20 | 0.48 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11223144 | 0.85 | BCAT2 (0.52) | BCAT2SGMS2HPGDCYP3A4CYP2C9 | |
| SCHEMBL8954968 | 0.78 | BCAT2 (0.59) | BCAT2HPGDCYP3A4CYP2C9MAPT | |
| SCHEMBL3481099 | 0.75 | TTR (0.41) | CYP1A2ALDH1A1HTTHSD17B10TDP1 | |
| SCHEMBL11594934 | 0.75 | SGMS2 (0.48) | BCAT2SGMS2HPGDCYP3A4CYP2C9 | |
| SCHEMBL9401757 | 0.74 | FABP4 (0.51) | BCAT2CYP2C9CYP1A2CYP2D6MAPT | |
| SCHEMBL11017137 | 0.74 | CDK2 (0.38) | CYP2C9KDM4ETDP1 | |
| SCHEMBL1170678 | 0.72 | KYNU (0.47) | CYP2C9MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL27489668 | 0.71 | AKR1C3 (0.42) | CYP3A4CYP2C9CYP1A2MAPTCYP2C19 | |
| SCHEMBL392794 | 0.70 | ALDH1A1 (0.59) | BCAT2HPGDCYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL7439162 | 0.70 | BCAT2 (0.73) | BCAT2HPGDCYP3A4CYP2C9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0036383-A1 | Process for the preparation of Beta-sulfato-ethylsulfonyl-aminobenzanilides | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-09-23 | — | — | EP | disclosed |