Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11147568 | 0.89 | BTK (0.39) | KCNH2LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL11446079 | 0.84 | KCNH2 (0.43) | KCNH2LMNAL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL11147256 | 0.75 | LMNA (0.42) | KCNH2LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL11439870 | 0.74 | KCNH2 (0.39) | KCNH2LMNAL3MBTL1BRD4KMT2A | |
| SCHEMBL2950629 | 0.73 | LMNA (0.71) | KCNH2LMNAL3MBTL1BRD4MEN1 | |
| SCHEMBL11150767 | 0.72 | KMT2A (0.41) | KCNH2LMNAL3MBTL1BRD4KMT2A | |
| SCHEMBL11148693 | 0.72 | KCNH2 (0.40) | KCNH2LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11148698 | 0.72 | KCNH2 (0.40) | KCNH2LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11148240 | 0.72 | OPRD1 (0.42) | LMNAL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL11149274 | 0.72 | POLB (0.43) | KCNH2LMNAL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0009683-A1 | Basic phenyl ethers, pharmaceutical compositions containing them and the preparation of these ethers and compositions | MERCK PATENT GmbH (DE) | 1980-04-16 | — | — | EP | disclosed |