Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 13/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 11/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 10/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PLD2 | O14939 | 1/20 | 0.37 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.37 |
| ▸ | ARRB1 | P49407 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11604012 | 0.84 | OPRM1 (0.47) | OPRK1OPRM1OPRD1OPRL1DRD3 | |
| SCHEMBL11454802 | 0.83 | HTR7 (0.52) | OPRK1OPRM1OPRD1OPRL1HTR7 | |
| SCHEMBL11455144 | 0.82 | OPRD1 (0.43) | OPRK1OPRM1OPRD1OPRL1DRD3 | |
| SCHEMBL11465183 | 0.82 | OPRD1 (0.43) | OPRK1OPRM1OPRD1OPRL1DRD3 | |
| SCHEMBL11447955 | 0.81 | OPRM1 (0.44) | OPRK1OPRM1OPRD1OPRL1DRD3 | |
| SCHEMBL11684188 | 0.72 | OPRM1 (0.63) | OPRK1OPRM1OPRD1OPRL1DRD3 | |
| SCHEMBL11457668 | 0.71 | ABCB1 (0.39) | OPRK1OPRM1OPRD1DRD3 | |
| SCHEMBL19475380 | 0.69 | OPRM1 (0.66) | OPRK1OPRM1OPRD1OPRL1DRD3 | |
| SCHEMBL9053106 | 0.69 | DRD3 (0.72) | OPRK1OPRM1OPRD1OPRL1DRD3 | |
| SCHEMBL11447147 | 0.69 | OPRM1 (0.46) | OPRK1OPRM1OPRD1OPRL1HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4205173-A | 1-Heterocyclic alkyl-1,2,3,4-tetrahydroquinazolinones and analgesic intermediates thereof | PENNWALT CORPORATION (US) | 1980-05-27 | — | — | US | disclosed |