Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.69 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | CDC7 | O00311 | 3/20 | 0.48 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768642 | 0.84 | ALDH1A1 (0.62) | ALOX5PTGS2KDM4EALDH1A1MAPT | |
| SCHEMBL9666309 | 0.83 | ALOX5 (0.58) | ALOX5PTGS2RAB9ANPC1KDM4E | |
| SCHEMBL11456658 | 0.83 | CDC7 (0.67) | PTGS2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL544650 | 0.82 | ALOX5 (0.55) | ALOX5PTGS2RAB9ANPC1KDM4E | |
| SCHEMBL9628580 | 0.82 | ALOX5 (1.00) | ALOX5RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL11460952 | 0.82 | RARA (0.56) | ALOX5PTGS2RAB9ANPC1KDM4E | |
| SCHEMBL15690527 | 0.82 | PTGS2 (0.54) | ALOX5PTGS2RAB9ANPC1KDM4E | |
| SCHEMBL514205 | 0.79 | ALOX5 (0.49) | ALOX5PTGS2KDM4EALDH1A1MAPT | |
| SCHEMBL10141083 | 0.79 | ALOX5 (0.49) | ALOX5PTGS2KDM4EALDH1A1MAPT | |
| SCHEMBL514204 | 0.79 | ALOX5 (0.49) | ALOX5PTGS2KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4197306-A | CONTROL OF INSECTS AND ACARIDS | UNIROYAL, INC. (US) | 1980-04-08 | — | — | US | disclosed |
| US-4153703-A | Method of controlling insects and acarids with certain aryl-substituted thiazoles | UNIROYAL, INC. (US) | 1979-05-08 | — | — | US | disclosed |