SCHEMBL1146681

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13596787	0.89	PDE8A (0.62)	YTHDC1PDE8APDE4APDE4BPDE4C
	SCHEMBL1146545	0.86	YTHDC1 (0.53)	YTHDC1PDE8APDE4APDE4BPDE4C
	SCHEMBL7204689	0.86	PDE8A (0.60)	YTHDC1PDE8APDE4APDE4BPDE4C
	SCHEMBL2060472	0.86	PDE4A (0.67)	YTHDC1PDE8APDE4APDE4BPDE4C
	SCHEMBL21076723	0.84	PDE8A (0.57)	YTHDC1PDE8APDE4APDE4BPDE4C
	SCHEMBL23764385	0.83	PDE8A (0.59)	YTHDC1PDE8APDE4APDE4BPDE4C
	SCHEMBL822875	0.83	PDE8A (0.56)	YTHDC1PDE8APDE4APDE4BPDE4C
	SCHEMBL17802599	0.82	CFTR (0.67)	YTHDC1PDE8APDE4DCDK1ADORA2A
	SCHEMBL2060105	0.82	PDE8A (0.55)	YTHDC1PDE8APDE4APDE4BPDE4C
	SCHEMBL25511872	0.81	MEN1 (0.59)	PDE8APDE4APDE4BPDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.