Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.52 |
| ▸ | FPR3 | P25089 | 1/20 | 0.52 |
| ▸ | FPR2 | P25090 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11477579 | 0.92 | FPR3 (0.46) | SIGMAR1FPR3FPR2ALDH1A1DRD2 | |
| SCHEMBL11460079 | 0.86 | EPHX1 (0.47) | SIGMAR1FPR3FPR2EPHX1CYP2D6 | |
| Ipexidine SCHEMBL11468017 | 0.75 | GNAI3 (0.52) | SIGMAR1FPR3FPR2SMN1; SMN2EPHX1 | |
| SCHEMBL10723940 | 0.72 | DRD2 (0.65) | SIGMAR1FPR3FPR2SMN1; SMN2DRD2 | |
| SCHEMBL491686 | 0.70 | SIGMAR1 (0.60) | SIGMAR1FPR3FPR2 | |
| SCHEMBL19849351 | 0.70 | SMN1; SMN2 (0.70) | SIGMAR1ALDH1A1SMN1; SMN2DRD2DRD3 | |
| SCHEMBL491685 | 0.70 | FPR3 (0.49) | SIGMAR1FPR3FPR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL11468030 | 0.69 | LMNA (0.40) | ALDH1A1SMN1; SMN2DRD2GAA | |
| Hydrochloric Acid SCHEMBL6347355 | 0.69 | FPR3 (0.48) | SIGMAR1FPR3FPR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL10724053 | 0.69 | ALDH1A1 (0.69) | SIGMAR1FPR3FPR2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4110328-A | Bis-carbamylguanidinoazaalkane antimicrobial compounds | COOPER LABORATORIES, INC. (US) | 1978-08-29 | — | — | US | claimed |
| US-4209624-A | Process for preparing substituted bis(amidinoureas) | COOPER LABORATORIES, INC. (US) | 1980-06-24 | — | — | US | disclosed |