Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11465335 | 0.83 | PTGS2 (0.58) | MTNR1BMTNR1ATSHRHPGDPTGS2 | |
| SCHEMBL14037607 | 0.79 | TSHR (0.55) | EPHX2NR1H4TSHRHPGDKMT2A | |
| SCHEMBL11463892 | 0.78 | HCAR3 (0.54) | TSHR | |
| SCHEMBL27711415 | 0.77 | EPHX2 (0.48) | EPHX2NR1H4TSHRHPGDKMT2A | |
| SCHEMBL7052993 | 0.77 | TSHR (0.57) | EPHX2NR1H4TSHRHPGDALOX15 | |
| SCHEMBL17198001 | 0.77 | TSHR (0.61) | EPHX2NR1H4TSHRALOX15MAPK1 | |
| SCHEMBL15660720 | 0.76 | RARB (0.54) | EPHX2NR1H4TSHRKMT2A | |
| SCHEMBL6559976 | 0.76 | LMNA (0.52) | HPGDHIF1A | |
| SCHEMBL25221325 | 0.76 | TSHR (0.55) | EPHX2NR1H4TSHRALOX15 | |
| SCHEMBL1010214 | 0.76 | MTNR1A (0.61) | MTNR1BMTNR1ATSHRHIF1ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4221815-A | HYPOGLYCEMIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-09-09 | — | — | US | disclosed |