Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 3/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CCR4 | P51679 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | TEK | Q02763 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11468337 | 0.86 | SLC6A4 (0.33) | CXCL8SLC6A4SLC6A2SLC6A3HTR2A | |
| SCHEMBL10926565 | 0.70 | TTR (0.42) | MAPTHPGDSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL5950358 | 0.69 | SLC6A2 (0.50) | CXCL8KDM4EMAPK1SLC6A4SLC6A2 | |
| SCHEMBL7765702 | 0.67 | CXCL8 (0.64) | CXCL8ALDH1A1HPGDKDM4EMAPK1 | |
| SCHEMBL11552165 | 0.66 | LMNA (0.44) | ALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL28291119 | 0.63 | CA1 (0.52) | ALDH1A1MAPK1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL22372364 | 0.63 | L3MBTL1 (0.47) | ALDH1A1MAPTHPGDKDM4ESLC6A4 | |
| SCHEMBL194417 | 0.63 | HRH1 (0.60) | ALDH1A1HPGDSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL22372361 | 0.62 | KDM4E (0.42) | ALDH1A1MAPTHPGDKDM4ESLC6A4 | |
| SCHEMBL4820216 | 0.62 | HTR2A (0.41) | ALDH1A1KDM4EMAPK1SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4201780-A | Mono-5-substituted-3-chloro-4H-1,2,6-thiadiazin-4-one antifungal agents | FMC CORPORATION (US) | 1980-05-06 | — | — | US | disclosed |