Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | PTGES | O14684 | 2/20 | 0.48 |
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11477306 | 0.88 | GPR84 (0.51) | GPR84MAPTRAB9AL3MBTL1TP53 | |
| SCHEMBL11477154 | 0.87 | GPR84 (0.67) | GPR84MAPTL3MBTL1PTGESCASP3 | |
| SCHEMBL11482987 | 0.84 | GPR84 (0.62) | GPR84MAPTRAB9AL3MBTL1TP53 | |
| SCHEMBL11241755 | 0.82 | CACNA2D1 (0.47) | GPR84MAPTRAB9ATP53CACNA2D1 | |
| SCHEMBL11485851 | 0.80 | TP53 (0.54) | GPR84MAPTRAB9ATP53CACNA2D1 | |
| SCHEMBL11485827 | 0.77 | PTGES (0.79) | MAPTRAB9AL3MBTL1TP53PTGES | |
| SCHEMBL11467121 | 0.76 | GPR84 (0.49) | GPR84MAPTRAB9AL3MBTL1TP53 | |
| SCHEMBL12285602 | 0.76 | MAPT (0.68) | MAPTRAB9AL3MBTL1TP53CASP3 | |
| SCHEMBL11484157 | 0.76 | LMNA (0.49) | GPR84MAPTTP53CACNA2D1ALDH1A1 | |
| SCHEMBL11468338 | 0.75 | PTGES (0.53) | GPR84MAPTL3MBTL1PTGESCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4190725-A | ANTIINFLAMMATORY | ELI LILLY AND COMPANY (US) | 1980-02-26 | — | — | US | disclosed |
| US-4021553-A | 5,6-Diaryl-1,2,4-triazines as topically-active anti-inflammatory agents | ELI LILLY AND COMPANY (US) | 1977-05-03 | — | — | US | disclosed |