SCHEMBL114709

SCHEMBL114709

CC1=Nc2ccc(S(=O)(=O)O)cc2C1(C)CCCS(=O)(=O)O

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31
RXRG P48443 1/20 0.31
SNCA P37840 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL136845 1.00 RXRA (0.31) RXRARXRBRXRGSNCA
Potassium SCHEMBL9929144 0.99 RXRA (0.30) RXRARXRBRXRG
SCHEMBL9929142 0.99 RXRA (0.30) RXRARXRBRXRG
SCHEMBL29017325 0.99 RXRA (0.30) RXRARXRBRXRG
SCHEMBL560182 0.96 RXRA (0.30) RXRARXRBRXRG
SCHEMBL15129781 0.95 RXRA (0.30) RXRARXRBRXRG
SCHEMBL10037955 0.88 S1PR3 (0.36) RXRARXRBRXRGSNCA
SCHEMBL17827213 0.87
SCHEMBL560019 0.86 CA2 (0.31) RXRARXRBRXRG
SCHEMBL15628865 0.85 CYP26B1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116239893-B Quaternary ammonium salt modified cyanine fluorescent dye and its synthesis and application 大连理工大学 2024-07-09 CN disclosed
CN-116239893-A Quaternary ammonium salt modified cyanine fluorescent dye and its synthesis and application 大连理工大学 2023-06-09 CN disclosed
US-11624089-B2 Cyanine dyes PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2023-04-11 US disclosed
US-11053222-B2 Fluorescent compounds PIERCE BIOTECHNOLOGY, INC. (US) 2021-07-06 US disclosed
US-20200232023-A1 CYANINE DYES PACIFIC BIOSCIENCES OF CALIFORNIA, INC. 2020-07-23 US disclosed
US-10696653-B2 Cyanine compounds PIERCE BIOTECHNOLOGY, INC. (US) 2020-06-30 US disclosed
US-10392659-B2 Cyanine dyes PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2019-08-27 US disclosed
US-10351551-B2 Fluorescent compounds PIERCE BIOTECHNOLOGY, INC. (US) 2019-07-16 US disclosed
US-10351551-B2 Fluorescent compounds PIERCE BIOTECHNOLOGY, INC. (US) 2019-07-16 US disclosed
CN-104395306-B The indole derivatives of labeling dye as biomolecule 皮尔斯生物科技有限公司 2019-04-23 CN disclosed
US-20120058469-A1 FUNCTIONALIZED CYANINE DYES (PEG) PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2012-03-08 US disclosed
EP-2426488-A1 MEASUREMENT METHOD UTILIZING INTERNAL STANDARD SUBSTANCE Wako Pure Chemical Industries, Ltd. (JP) 2012-03-07 EP disclosed
EP-2426123-A1 PYRAZOLE-BASED CYANINE DYE CONTAINING QUATERNARY AMMONIUM CATION Wako Pure Chemical Industries, Ltd. (JP) 2012-03-07 EP disclosed
WO-2012027623-A2 CYANINE DYES PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2012-03-01 WO disclosed
US-20120052506-A1 CYANINE DYES PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2012-03-01 US disclosed
WO-2012027618-A2 FUNCTIONALIZED CYANINE DYES PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2012-03-01 WO disclosed
US-20120043207-A1 MEASUREMENT METHOD UTILIZING INTERNAL STANDARD SUBSTANCE WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2012-02-23 US disclosed
US-20120046474-A1 PYRAZOLE-BASED CYANINE DYE CONTAINING QUATERNARY AMMONIUM CATION WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2012-02-23 US disclosed
US-20090069546-A1 PYRAZOLE-BASED CYANINE DYE WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2009-03-12 US disclosed
EP-2006289-A1 PYRAZOLE-TYPE CYANINE DYE Wako Pure Chemical Industries, Ltd. (JP) 2008-12-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10392659-B2 Cyanine dyes ABCG2, IK, ACR RXRA 2390/4885RXRB 2432/4885RXRG 1959/4885
US-20090069546-A1 PYRAZOLE-BASED CYANINE DYE CBR3, CYB5R3, TST RXRA 2901/4885RXRB 2618/4885RXRG 3032/4885
US-20120046474-A1 PYRAZOLE-BASED CYANINE DYE CONTAINING QUATERNARY AMMONIUM CATION SLC43A1, HCN4, SLC7A5 RXRA 4202/4885RXRB 4462/4885RXRG 4584/4885
US-10351551-B2 Fluorescent compounds NCL, FUS, EFTUD2 RXRA 2225/4885RXRB 2348/4885RXRG 1868/4885
US-11624089-B2 Cyanine dyes ABCG2, IK, ACR RXRA 2390/4885RXRB 2432/4885RXRG 1959/4885
US-10696653-B2 Cyanine compounds NCL, NOP58, NAT10 RXRA 3347/4885RXRB 3459/4885RXRG 3097/4885
US-20120052506-A1 CYANINE DYES ABCG2, IK, ACR RXRA 2390/4885RXRB 2432/4885RXRG 1959/4885
US-20200232023-A1 CYANINE DYES ABCG2, IK, ACR RXRA 2390/4885RXRB 2432/4885RXRG 1959/4885
US-11053222-B2 Fluorescent compounds NCL, FUS, EFTUD2 RXRA 2225/4885RXRB 2348/4885RXRG 1868/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.