SCHEMBL560182

SCHEMBL560182

CC1=Nc2ccc(S(=O)(=O)O)cc2C1(C)CCCCS(=O)(=O)O

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.30
RXRB P28702 1/20 0.30
RXRG P48443 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15129781 0.99 RXRA (0.30) RXRARXRBRXRG
SCHEMBL114709 0.96 RXRA (0.31) RXRARXRBRXRG
SCHEMBL136845 0.96 RXRA (0.31) RXRARXRBRXRG
SCHEMBL29017325 0.95 RXRA (0.30) RXRARXRBRXRG
SCHEMBL9929142 0.95 RXRA (0.30) RXRARXRBRXRG
Potassium SCHEMBL9929144 0.95 RXRA (0.30) RXRARXRBRXRG
SCHEMBL24284312 0.88
SCHEMBL560019 0.88 CA2 (0.31) RXRARXRBRXRG
SCHEMBL10037955 0.87 S1PR3 (0.36) RXRARXRBRXRG
SCHEMBL13264906 0.85 CYP26B1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11834489-B2 Methods for quantifying ligand efficacy in G-protein coupled receptors using single-molecule fluorescence energy transfer CORNELL UNIVERSITY (US) 2023-12-05 US disclosed
EP-3773750-B1 FORMULATION AND METHOD OF PREPARATION GE HEALTHCARE AS (NO) 2022-04-20 EP disclosed
US-20210046195-A1 FORMULATION AND METHOD OF PREPARATION GE HEALTHCARE AS (NO) 2021-02-18 US disclosed
US-20210046195-A1 FORMULATION AND METHOD OF PREPARATION GE HEALTHCARE AS (NO) 2021-02-18 US disclosed
CN-112203698-A Preparation and preparation method 通用电气医疗集团股份有限公司 2021-01-08 CN disclosed
US-9631096-B2 Dye compositions, methods of preparation, conjugates thereof, and methods of use CORNELL UNIVERSITY (US) 2017-04-25 US disclosed
US-9110069-B2 Luminescent compounds SETA BIOMEDICALS, LLC (US) 2015-08-18 US disclosed
US-9110069-B2 Luminescent compounds SETA BIOMEDICALS, LLC (US) 2015-08-18 US disclosed
US-20150011731-A1 DYE COMPOSITIONS, METHODS OF PREPARATION, CONJUGATES THEREOF, AND METHODS OF USE CORNELL UNIVERSITY (US) 2015-01-08 US disclosed
US-20140086844-A1 LUMINESCENT COMPOUNDS SETA BIOMEDICALS, LLC (US) 2014-03-27 US disclosed
US-20070203343-A1 Cyanine Dye Labelling Reagents GE HEALTHCARE UK LIMITED (GB) 2007-08-30 US disclosed
US-20070203343-A1 Cyanine Dye Labelling Reagents GE HEALTHCARE UK LIMITED (GB) 2007-08-30 US disclosed
US-20060239922-A1 WATER-SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS GE HEALTHCARE UK LIMITED (GB) 2006-10-26 US disclosed
WO-2006111726-A1 WATER SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS GE HEALTHCARE UK LIMITED (GB) 2006-10-26 WO disclosed
EP-1678258-A1 CYANINE DYE LABELLING REAGENTS GE Healthcare Limited (GB) 2006-07-12 EP disclosed
US-20060051758-A1 Chiral indole intermediates and their fluorescent cyanine dyes containing functional groups NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2006-03-09 US disclosed
EP-1525265-A4 CHIRAL INDOLE INTERMEDIATES AND THEIR FLUORESCENT CYANINE DYES CONTAINING FUNCTIONAL GROUPS UNIV CARNEGIE MELLON (US) 2005-06-22 EP disclosed
WO-2005044923-A1 CYANINE DYE LABELLING REAGENTS GE HEALTHCARE LIMITED (GB) 2005-05-19 WO disclosed
EP-1525265-A2 CHIRAL INDOLE INTERMEDIATES AND THEIR FLUORESCENT CYANINE DYES CONTAINING FUNCTIONAL GROUPS CARNEGIE-MELLON UNIVERSITY (US) 2005-04-27 EP disclosed
WO-2004039894-A2 CHIRAL INDOLE INTERMEDIATES AND THEIR FLUORESCENT CYANINE DYES CONTAINING FUNCTIONAL GROUPS CARNEGIE MELLON UNIVERSITY (US) 2004-05-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210046195-A1 FORMULATION AND METHOD OF PREPARATION IAPP, LPXN, KIT RXRA 3815/4885RXRB 3195/4885RXRG 3093/4885
US-20140086844-A1 LUMINESCENT COMPOUNDS PHOSPHO1, PGLS, PFAS RXRA 4546/4885RXRB 4432/4885RXRG 4665/4885
US-20060051758-A1 Chiral indole intermediates and their fluorescent cyanine dyes containing functional groups IDO1, TDO2, IDO2 RXRA 2790/4885RXRB 2980/4885RXRG 2264/4885
US-20060239922-A1 WATER-SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS TPD52L2, MRPL21, MRPL9 RXRA 1256/4885RXRB 1103/4885RXRG 1188/4885
US-20070203343-A1 Cyanine Dye Labelling Reagents IK, H1-5, H1-3 RXRA 1726/4885RXRB 1654/4885RXRG 1474/4885
US-11834489-B2 Methods for quantifying ligand efficacy in G-protein coupled receptors using single-molecule fluorescence energy transfer GPR3, GPR4, GPR68 RXRA 1032/4885RXRB 873/4885RXRG 638/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.