Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CLK1 | P49759 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3247108 | 0.88 | MAPT (0.51) | KCNH2ALDH1A1MAPTHTTCLK1 | |
| SCHEMBL1147533 | 0.88 | KCNH2 (0.60) | KCNH2ALDH1A1MAPTHTTCLK1 | |
| SCHEMBL3253530 | 0.81 | KCNH2 (0.52) | KCNH2ALDH1A1MAPTHTTCLK1 | |
| SCHEMBL3126601 | 0.79 | KCNH2 (0.67) | KCNH2 | |
| SCHEMBL1147911 | 0.79 | TRPV1 (0.46) | KCNH2ALDH1A1HTTSMN1; SMN2MTNR1B | |
| SCHEMBL3251040 | 0.79 | MTNR1B (0.53) | ALDH1A1NPSR1MTNR1BMTNR1AKDM4E | |
| SCHEMBL3251044 | 0.79 | MTNR1B (0.53) | ALDH1A1NPSR1MTNR1BMTNR1AKDM4E | |
| SCHEMBL1147940 | 0.77 | MAPT (0.51) | KCNH2ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL1147941 | 0.77 | MAPT (0.51) | KCNH2ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL3244126 | 0.77 | KCNH2 (0.49) | KCNH2ALDH1A1MAPTHTTCLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250057962-A1 | PROCESSABLE COMPOSITIONS AND USE FOR THE SAME | RIPPLE THERAPEUTICS CORPORATION (CA) | 2025-02-20 | — | — | US | claimed |
| EP-4426712-A1 | PROCESSABLE COMPOSITIONS AND USE FOR THE SAME | Ripple Therapeutics Corporation (CA) | 2024-09-11 | — | — | EP | claimed |
| WO-2023079362-A1 | PROCESSABLE COMPOSITIONS AND USE FOR THE SAME | RIPPLE THERAPEUTICS CORPORATION (CA) | 2023-05-11 | — | — | WO | claimed |
| US-20190038622-A1 | NEUROPROTECTIVE AGENTS FOR TREATMENT OF NEURODEGENERATIVE DISEASES | WAYNE STATE UNIVERSITY | 2019-02-07 | — | — | US | claimed |
| US-20120196825-A1 | COMPOSITIONS AND METHODS FOR MODULATING THE IMMUNE SYSTEM | SUPPORTIVE THERAPEUTICS AG (CH) | 2012-08-02 | — | — | US | claimed |
| US-20090156546-A1 | Compositions and methods for modulating the immune system | SUPPORTIVE THERAPEUTICS AG (CH) | 2009-06-18 | — | — | US | claimed |
| EP-2026810-A2 | COMPOSITIONS AND METHODS FOR MODULATING THE IMMUNE SYSTEM | Prendergast, Patrick T. (AU) | 2009-02-25 | — | — | EP | claimed |
| US-20080027129-A1 | Administration of 3H-1, 2-dithiole-3-thione, anethole dithiolethione, sulforaphane, phenethyl isothiocyanate, 6-(methylsulfinyl)hexyl isothiocyanate and allyl isothiocyanate for the treatment of canities | L'OREAL (FR) | 2008-01-31 | — | — | US | claimed |
| EP-1872769-A1 | Use of 3h-1,2-dithiole-3-thione, anethole dithiolethione, sulforaphane, phenethyl isothiocyanate, 6-methyl-sulphinyl)hexyl isothiocyanate and allyl isothiocyanate for treating whitening of the hair | L'OREAL (FR) | 2008-01-02 | — | — | EP | claimed |
| EP-1858875-A2 | ANETHOLE DITHIOLETHIONE AND OTHER DITHIOLETHIONES FOR THE TREATMENT OF CONDITIONS ASSOCIATED WITH DYSFUNCTION OF MONOAMINE NEUROTRANSMISSION | Solvay Pharmaceuticals B.V. (NL) | 2007-11-28 | — | — | EP | claimed |
| WO-2007131973-A2 | COMPOSITIONS AND METHODS FOR MODULATING THE IMMUNE SYSTEM | PRENDERGAST PATRICK T (AU) | 2007-11-22 | — | — | WO | claimed |
| US-20060194971-A1 | Anethole dithiolethione and other dithiolethiones for the treatment of conditions associated with dysfunction of monoamine neruotransmission | SOLVAY PHARMACEUTICALS B.V. (NL) | 2006-08-31 | — | — | US | claimed |
| WO-2006089861-A2 | ANETHOLE DITHIOLETHIONE AND OTHER DITHIOLETHIONES FOR THE TREATMENT OF CONDITIONS ASSOCIATED WITH DYSFUNCTION OF MONOAMINE NEUROTRANSMISSION | SOLVAY PHARMACEUTICALS B.V. (NL) | 2006-08-31 | — | — | WO | claimed |
| US-7012148-B2 | Compositions and methods for thionation during chemical synthesis reactions | TRUSTEES OF DARTMOUTH COLLEGE (US) | 2006-03-14 | — | — | US | claimed |
| US-20030176714-A1 | Compositions and methods for thionation during chemical synthesis reactions | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-09-18 | — | — | US | claimed |
| WO-2002026909-A1 | COMPOSITIONS AND METHODS FOR THIONATION DURING CHEMICAL SYNTHESIS REACTIONS | TRUSTEES OF DARTMOUTH COLLEGE (US) | 2002-04-04 | — | — | WO | claimed |
| US-20250057962-A1 | PROCESSABLE COMPOSITIONS AND USE FOR THE SAME | RIPPLE THERAPEUTICS CORPORATION (CA) | 2025-02-20 | — | — | US | disclosed |
| EP-4426712-A1 | PROCESSABLE COMPOSITIONS AND USE FOR THE SAME | Ripple Therapeutics Corporation (CA) | 2024-09-11 | — | — | EP | disclosed |
| WO-2002026909-A1 | COMPOSITIONS AND METHODS FOR THIONATION DURING CHEMICAL SYNTHESIS REACTIONS | TRUSTEES OF DARTMOUTH COLLEGE (US) | 2002-04-04 | — | — | WO | disclosed |
| WO-2000056299-A2 | THE USE OF AMIFOSTINE FOR THE PROTECTION AGAINST TUMOR METASTASIS FORMATION | ARCH DEVELOPMENT CORPORATION (US) | 2000-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250057962-A1 | PROCESSABLE COMPOSITIONS AND USE FOR THE SAME | CCND2, CCND1, C9 | KCNH2 2116/4885ALDH1A1 2326/4885MAPT 583/4885 |
| US-20080027129-A1 | Administration of 3H-1, 2-dithiole-3-thione, anethole dithiolethione, sulforaphane, phenethyl isothiocyanate, 6-(methylsulfinyl)hexyl isothiocyanate and allyl isothiocyanate for the treatment of canities | TST, CTH, NOTUM | KCNH2 2532/4885ALDH1A1 603/4885MAPT 2487/4885 |
| US-20060194971-A1 | Anethole dithiolethione and other dithiolethiones for the treatment of conditions associated with dysfunction of monoamine neruotransmission | MAOB, MAOA, DAO | KCNH2 3287/4885ALDH1A1 263/4885MAPT 2908/4885 |
| US-20030176714-A1 | Compositions and methods for thionation during chemical synthesis reactions | TST, TPMT, MTAP | KCNH2 3006/4885ALDH1A1 2028/4885MAPT 1401/4885 |
| US-20190038622-A1 | NEUROPROTECTIVE AGENTS FOR TREATMENT OF NEURODEGENERATIVE DISEASES | SMN1; SMN2, PARK7, SNCA | KCNH2 434/4885ALDH1A1 1481/4885MAPT 409/4885 |
| US-20090156546-A1 | Compositions and methods for modulating the immune system | MRE11, XPA, MPL | KCNH2 3331/4885ALDH1A1 3955/4885MAPT 4639/4885 |
| US-20120196825-A1 | COMPOSITIONS AND METHODS FOR MODULATING THE IMMUNE SYSTEM | MRE11, XPA, MPL | KCNH2 3331/4885ALDH1A1 3955/4885MAPT 4639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.