SCHEMBL11485652

SCHEMBL11485652

CC(C)(C)c1ccc(Nc2cccc(Cl)c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF3 O95398 1/20 0.47
RAPGEF4 Q8WZA2 1/20 0.47
CNR1 P21554 1/20 0.47
FADS1 O60427 2/20 0.45
KMT2A Q03164 4/20 0.43
MEN1 O00255 3/20 0.43
GAA P10253 1/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
LMNA P02545 2/20 0.43
GRIN2B Q13224 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
KIF11 P52732 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
MAPT P10636 3/20 0.42
ALDH1A1 P00352 2/20 0.42
AR P10275 1/20 0.42
HTT P42858 1/20 0.42
GSK3B P49841 1/20 0.41
TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29945226 1.00 RAPGEF3 (0.47) RAPGEF3RAPGEF4CNR1FADS1KMT2A
SCHEMBL22050052 0.87 MAPT (0.56) CNR1KMT2AMEN1GAANPC1
SCHEMBL25382323 0.86 FADS1 (0.44) RAPGEF3RAPGEF4CNR1FADS1KMT2A
SCHEMBL25828041 0.86 FADS1 (0.44) RAPGEF3RAPGEF4CNR1FADS1KMT2A
SCHEMBL30365006 0.83 KIF11 (0.56) KMT2AMEN1NPC1RAB9ALMNA
SCHEMBL21252630 0.83 KIF11 (0.56) KMT2AMEN1NPC1RAB9ALMNA
SCHEMBL26430303 0.83 GAA (0.54) RAPGEF3RAPGEF4CNR1KMT2AMEN1
SCHEMBL26316048 0.82 P2RX1 (0.50) CNR1KMT2AMEN1GAANPC1
SCHEMBL27338901 0.81 NPC1 (0.59) CNR1KMT2AMEN1GAANPC1
SCHEMBL1686631 0.80 FADS1 (0.59) FADS1KMT2AMEN1GAANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240155945-A1 HIGHLY EFFICIENT BLUE FLUORESCENT ORGANIC EMITTER HAVING A HIGH HOMO LEVEL AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME IDEMITSU KOSAN CO.,LTD. (JP) 2024-05-09 US disclosed
EP-4349934-A1 A HIGHLY EFFICIENT BLUE FLUORESCENT ORGANIC EMITTER HAVING A HIGH HOMO LEVEL AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME Idemitsu Kosan Co., Ltd (JP) 2024-04-10 EP disclosed
EP-3909958-B1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEMICAL LTD (KR) 2023-12-27 EP disclosed
CN-113906580-B Organic light-emitting element 株式会社LG化学 2023-12-08 CN disclosed
US-20230329109-A1 POLYCYCLIC AROMATIC DERIVATIVE COMPOUND AND ORGANOELECTROLUMINESCENT DEVICE USING SAME SFC CO., LTD. (KR) 2023-10-12 US disclosed
US-20230329109-A1 POLYCYCLIC AROMATIC DERIVATIVE COMPOUND AND ORGANOELECTROLUMINESCENT DEVICE USING SAME SFC CO., LTD. (KR) 2023-10-12 US disclosed
US-20230279027-A1 LIGHT EMITTING ELEMENT AND POLYCYCLIC COMPOUND FOR LIGHT EMITTING ELEMENT SAMSUNG DISPLAY CO., LTD. (KR) 2023-09-07 US disclosed
US-20230279027-A1 LIGHT EMITTING ELEMENT AND POLYCYCLIC COMPOUND FOR LIGHT EMITTING ELEMENT SAMSUNG DISPLAY CO., LTD. (KR) 2023-09-07 US disclosed
US-20230279027-A1 LIGHT EMITTING ELEMENT AND POLYCYCLIC COMPOUND FOR LIGHT EMITTING ELEMENT SAMSUNG DISPLAY CO., LTD. (KR) 2023-09-07 US disclosed
CN-116693560-A Light-emitting element and polycyclic compound for light-emitting element 三星显示有限公司 2023-09-05 CN disclosed
EP-4202011-A1 POLYCYCLIC AROMATIC DERIVATIVE COMPOUND AND ORGANOELECTROLUMINESCENT DEVICE USING SAME SFC Co., Ltd. (KR) 2023-06-28 EP disclosed
CN-112876498-B Polycyclic aromatic compound and organic electroluminescent element containing same 北京八亿时空液晶科技股份有限公司 2023-04-18 CN disclosed
US-20230114182-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-04-13 US disclosed
CN-113366002-B Compound and organic light emitting device including the same 株式会社LG化学 2022-09-27 CN disclosed
US-20220089617-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2022-03-24 US disclosed
CN-113906580-A Organic light emitting element 株式会社LG化学 2022-01-07 CN disclosed
EP-3909958-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG Chem, Ltd. (KR) 2021-11-17 EP disclosed
CN-113366002-A Compound and organic light emitting device including the same 株式会社LG化学 2021-09-07 CN disclosed
CN-112876498-A Polycyclic aromatic compound and organic electroluminescent element containing the same 北京八亿时空液晶科技股份有限公司 2021-06-01 CN disclosed
US-4216214-A ANTISECRETORY AGENTS PRODESIN (PRODUCTOS ESTEVE INTERNACIONAL S.A.) (ES) 1980-08-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230279027-A1 LIGHT EMITTING ELEMENT AND POLYCYCLIC COMPOUND FOR LIGHT EMITTING ELEMENT CRY1, NR2E3, NFE2L2 RAPGEF3 3807/4885RAPGEF4 1997/4885CNR1 4188/4885
US-20220089617-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME CRY1, CYP1A1, CYP1B1 RAPGEF3 4665/4885RAPGEF4 4158/4885CNR1 618/4885
US-20230329109-A1 POLYCYCLIC AROMATIC DERIVATIVE COMPOUND AND ORGANOELECTROLUMINESCENT DEVICE USING SAME DDT, UROD, DDC RAPGEF3 3418/4885RAPGEF4 2139/4885CNR1 3880/4885
US-20230114182-A1 ORGANIC LIGHT EMITTING DEVICE CRY1, CRY2, NR2E3 RAPGEF3 4423/4885RAPGEF4 3721/4885CNR1 3975/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.