Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | JUN | P05412 | 1/20 | 0.46 |
| ▸ | TFEB | P19484 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GSR | P00390 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5598954 | 0.85 | NFE2L2 (0.61) | NFE2L2NFKB1JUNTFEBHSD11B1 | |
| SCHEMBL5598952 | 0.85 | NFE2L2 (0.61) | NFE2L2NFKB1JUNTFEBHSD11B1 | |
| SCHEMBL11471846 | 0.79 | GSR (0.65) | NFE2L2NFKB1JUNRAB9AALDH1A1 | |
| SCHEMBL608507 | 0.77 | JUN (0.54) | NFE2L2NFKB1JUNTFEBHSD11B1 | |
| SCHEMBL78556 | 0.76 | CA1 (0.62) | NFKB1RAB9AALDH1A1TSHRLMNA | |
| SCHEMBL2425317 | 0.76 | CA1 (0.62) | NFKB1RAB9AALDH1A1TSHRLMNA | |
| SCHEMBL31422587 | 0.76 | MAPT (0.66) | NFE2L2NFKB1JUNTFEBHSD11B1 | |
| SCHEMBL7899013 | 0.76 | MAPT (0.66) | NFE2L2NFKB1JUNTFEBHSD11B1 | |
| SCHEMBL2834883 | 0.76 | MAPT (0.66) | NFE2L2NFKB1JUNTFEBHSD11B1 | |
| SCHEMBL78555 | 0.76 | CA1 (0.62) | NFKB1RAB9AALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4233440-A | OPTICAL BRIGHTENERS | BAYER AKTIENGESELLSCHAFT (DE) | 1980-11-11 | — | — | US | disclosed |