Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.37 |
| ▸ | ABAT | P80404 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4259186 | 0.80 | ALDH1A1 (0.64) | TSHRMAPK1ALDH1A1GPR35TP53 | |
| SCHEMBL8317335 | 0.78 | TDP1 (0.64) | TSHRALDH1A1GPR35ALOX15L3MBTL1 | |
| SCHEMBL11520066 | 0.78 | MAPK1 (0.59) | TSHRMAPK1ALDH1A1L3MBTL1TDP1 | |
| SCHEMBL8316198 | 0.78 | VCAM1 (0.56) | TSHRMAPK1HSD17B10TDP1 | |
| SCHEMBL9793637 | 0.78 | ALOX15 (0.66) | TSHRMAPK1ALDH1A1ALOX15L3MBTL1 | |
| SCHEMBL8192824 | 0.75 | KIF11 (0.49) | TSHRMAPK1ALDH1A1TP53HPGD | |
| SCHEMBL8187684 | 0.74 | ALDH1A1 (0.55) | TSHRMAPK1ALDH1A1HPGDALOX15 | |
| SCHEMBL2447568 | 0.74 | ALDH1A1 (0.57) | TSHRMAPK1ALDH1A1GPR35TP53 | |
| SCHEMBL4056837 | 0.74 | VCAM1 (0.64) | MAPK1HPGDTDP1MAPTMEN1 | |
| SCHEMBL11258868 | 0.74 | ALDH1A1 (0.55) | MAPK1ALDH1A1HPGDSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4220602-A | FOR HAIR COSMETICS | L'OREAL (FR) | 1980-09-02 | — | — | US | disclosed |