Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.64 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.57 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.57 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PTPRC | P08575 | 1/20 | 0.45 |
| ▸ | S100A4 | P26447 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11496559 | 0.80 | TSHR (0.41) | ALDH1A1TSHRMAPK1GPR35TP53 | |
| SCHEMBL600206 | 0.79 | TDP1 (0.68) | ALDH1A1TSHRMAPK1GPR35TP53 | |
| SCHEMBL29809877 | 0.79 | TDP1 (0.68) | ALDH1A1TSHRMAPK1GPR35TP53 | |
| 2,4-Dinitrophenol SCHEMBL27880483 | 0.79 | GPR35 (0.92) | ALDH1A1TSHRMAPK1GPR35TP53 | |
| 2,4-Dinitrophenol SCHEMBL29361027 | 0.78 | GPR35 (1.00) | ALDH1A1TSHRMAPK1GPR35TP53 | |
| 2,4-Dinitrophenol SCHEMBL1517938 | 0.78 | GPR35 (1.00) | ALDH1A1TSHRMAPK1GPR35TP53 | |
| 2,4-Dinitrophenol SCHEMBL77643 | 0.78 | GPR35 (1.00) | ALDH1A1TSHRMAPK1GPR35TP53 | |
| SCHEMBL5958796 | 0.77 | TDP1 (0.65) | ALDH1A1TSHRMAPK1GPR35TP53 | |
| SCHEMBL11640997 | 0.77 | ALDH1A1 (0.47) | ALDH1A1TSHRMAPK1GPR35TP53 | |
| SCHEMBL4054277 | 0.77 | ALDH1A1 (0.67) | ALDH1A1TSHRMAPK1GPR35TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116019794-A | Application of amino fullerene material in preparation of exosome PD-L1 inhibition drugs | 中国科学院化学研究所 | 2023-04-28 | — | — | CN | claimed |
| CN-107698567-B | Isatin azole alcohol compound and preparation method and medical application thereof | 西南大学 | 2020-09-15 | — | — | CN | claimed |
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | claimed |
| EP-1504094-A2 | PEPTIDE COMPOUNDS AND THEIR USE AS PROTEASE SUBSTRATES | Pharmacia Corporation (US) | 2005-02-09 | — | — | EP | claimed |
| US-20040018561-A1 | Peptide compounds and their use as protease substrates | PHARMACIA CORPORATION | 2004-01-29 | — | — | US | claimed |
| WO-2003095475-A2 | PEPTIDE COMPOUNDS AND THEIR USE AS PROTEASE SUBSTRATES | PHARMACIA CORPORATION (US) | 2003-11-20 | — | — | WO | claimed |
| US-5994430-A | POLYMER CONTAINING A UNSATURATED PHENOL COMPOUND | CLARIANT FINANCE BVI) LIMITED (VG) | 1999-11-30 | — | — | US | claimed |
| EP-0546113-A1 | NONLINEAR OPTICAL MATERIALS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-06-16 | — | — | EP | claimed |
| WO-1992003417-A2 | NONLINEAR OPTICAL MATERIALS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-03-05 | — | — | WO | claimed |
| US-4213898-A | FOR POLYACRYLONITRILE | SANDOZ LTD. (CH) | 1980-07-22 | — | — | US | claimed |
| US-4097665-A | Diacylnucleosides and process for preparing the same | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) | 1978-06-27 | — | — | US | claimed |
| US-4011208-A | 3-CYANO OR ACYL-4-ARYL-5-ARYLAZO-6-HYDROXYPYRIDONE-2 DYES | SANDOZ LTD. (CH) | 1977-03-08 | — | — | US | claimed |
| US-3998803-A | TEXTILES | FIDELITY UNION TRUST COMPANY, EXECUTIVE TRUSTEE UNDER THE SANDOZ TRUST (US) | 1976-12-21 | — | — | US | claimed |
| CN-116019794-A | Application of amino fullerene material in preparation of exosome PD-L1 inhibition drugs | 中国科学院化学研究所 | 2023-04-28 | — | — | CN | disclosed |
| EP-3037428-B1 | MACROLIDE COMPOUND | PULIKE BIOLOGICAL ENG INC (CN) | 2020-09-23 | — | — | EP | disclosed |
| CN-107698567-B | Isatin azole alcohol compound and preparation method and medical application thereof | 西南大学 | 2020-09-15 | — | — | CN | disclosed |
| US-4011208-A | 3-CYANO OR ACYL-4-ARYL-5-ARYLAZO-6-HYDROXYPYRIDONE-2 DYES | SANDOZ LTD. (CH) | 1977-03-08 | — | — | US | disclosed |
| US-3998803-A | TEXTILES | FIDELITY UNION TRUST COMPANY, EXECUTIVE TRUSTEE UNDER THE SANDOZ TRUST (US) | 1976-12-21 | — | — | US | disclosed |
| US-3985737-A | ANTIBACTERIAL AGENTS | ELI LILLY AND COMPANY (US) | 1976-10-12 | — | — | US | disclosed |
| US-3962227-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1976-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040018561-A1 | Peptide compounds and their use as protease substrates | MMP3, MMP25, MMP11 | ALDH1A1 3443/4885TSHR 3786/4885MAPK1 848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.