Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 8/20 | 0.47 |
| ▸ | MAOA | P21397 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11553593 | 0.81 | ALDH1A1 (0.45) | MAPTSMN1; SMN2MAOBMAOARAB9A | |
| SCHEMBL11550765 | 0.81 | TP53 (0.37) | MAPTSMN1; SMN2MEN1KMT2AMAOB | |
| SCHEMBL11548529 | 0.80 | TP53 (0.36) | MAPTSMN1; SMN2MEN1KMT2AMAOB | |
| SCHEMBL10452829 | 0.78 | KDM4E (0.61) | MAPTSMN1; SMN2MEN1KMT2AMAOA | |
| SCHEMBL11548259 | 0.78 | NISCH (0.50) | MAPTSMN1; SMN2MAOBMAOARAB9A | |
| SCHEMBL11503586 | 0.76 | ALOX15 (0.34) | MAPTSMN1; SMN2MAOBMAOARAB9A | |
| SCHEMBL28172130 | 0.76 | RAB9A (0.67) | MAPTSMN1; SMN2MEN1KMT2AMAOB | |
| SCHEMBL29640433 | 0.76 | RAB9A (0.67) | MAPTSMN1; SMN2MEN1KMT2AMAOB | |
| SCHEMBL10452882 | 0.75 | KDM4E (0.57) | MAPTSMN1; SMN2MEN1KMT2AMAOB | |
| SCHEMBL10452923 | 0.74 | KDM4E (0.56) | MAPTSMN1; SMN2MEN1KMT2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151180-A | INTERMEDIATES FOR ANTIALLERGENS, ANTIHISTAMINES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-04-24 | — | — | US | disclosed |
| US-4116971-A | 3-(1H-TETRAZOL-5-YL)CHROMONES | WARNER-LAMBERT COMPANY (US) | 1978-09-26 | — | — | US | disclosed |