SCHEMBL1152098

SCHEMBL1152098

c1ccc(CNOc2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD4 P21917 1/20 0.48
KMT2A Q03164 3/20 0.47
MEN1 O00255 2/20 0.47
HTT P42858 1/20 0.47
IDO1 P14902 2/20 0.46
THRB P10828 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
CYP3A4 P08684 2/20 0.44
MAPT P10636 2/20 0.44
KDM4E B2RXH2 1/20 0.44
BCHE P06276 2/20 0.44
HPGD P15428 2/20 0.44
TSHR P16473 1/20 0.42
RECQL P46063 1/20 0.42
ADH1B P00325 1/20 0.41
ADH1C P00326 1/20 0.41
ADH1A P07327 1/20 0.41
ADH7 P40394 1/20 0.41
ALDH1A1 P00352 1/20 0.41
ALOX12 P18054 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9112489 0.98 MAPT (0.48) DRD4KMT2AMEN1HTTIDO1
SCHEMBL14195530 0.86 TP53 (0.48) DRD4KMT2AMEN1MAPTKDM4E
SCHEMBL9274672 0.86 MAPT (0.54) DRD4KMT2AMEN1HTTCYP3A4
SCHEMBL4671885 0.81 MAPK1 (0.49) KMT2AMEN1HTTTDP1MAPT
SCHEMBL14176789 0.81 RAB9A (0.47) KMT2AMEN1KDM4E
SCHEMBL1101359 0.77 GAA (0.53) DRD4KMT2AMEN1IDO1CYP3A4
SCHEMBL11661655 0.77 IDO1 (0.52) DRD4KMT2AMEN1HTTIDO1
SCHEMBL2126523 0.74 FABP1 (0.48) DRD4KMT2AMEN1IDO1THRB
SCHEMBL1045802 0.74 DRD2 (0.58) DRD4KMT2AMEN1BCHEHPGD
SCHEMBL507062 0.73 CA4 (0.42) TSHRMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11547115-B2 Wettable agrochemical composition NIPPON KAYUKU CO., LTD. (JP) 2023-01-10 US claimed
CN-113024389-B Preparation method of substituted phenoxybenzylamine compound and pyrazole carboxamide compound 山东海利尔化工有限公司 2021-08-31 CN claimed
CN-113164451-A Methods and compositions for treating glaucoma and related disorders 奥库菲尔制药股份有限公司 2021-07-23 CN claimed
CN-113164452-A Methods and compositions for treating presbyopia, mydriasis and other ocular disorders 奥库菲尔制药股份有限公司 2021-07-23 CN claimed
CN-113024389-A Preparation method of substituted phenoxybenzylamine compound and pyrazole carboxamide compound 山东海利尔化工有限公司 2021-06-25 CN claimed
CN-112292035-A Water-dispersible pesticide composition 日本化药株式会社 2021-01-29 CN claimed
CN-1374861-A Methods for modulating the human sexual response ZONAGEN INC (US) 2002-10-16 CN claimed
CN-117750948-A Compositions and methods for targeted systemic delivery to cells 瑞科德治疗公司 2024-03-22 CN disclosed
CN-117597327-A Pharmaceutical preparation 第一波动生物制药股份有限公司 2024-02-23 CN disclosed
CN-111848494-B Guanidine compounds and uses thereof 伊谬诺米特医疗有限公司 2023-08-01 CN disclosed
CN-110831584-B Targeted drug rescue with novel compositions, combinations and methods thereof 埃克塞瓦有限责任公司 2023-03-10 CN disclosed
US-11547115-B2 Wettable agrochemical composition NIPPON KAYUKU CO., LTD. (JP) 2023-01-10 US disclosed
CN-115216438-A Preparation method and application of engineering myocardial tissue based on big blue flashing butterfly wing 苏州大学 2022-10-21 CN disclosed
EP-0288515-A4 QUATERNIZED NITROGEN CONTAINING COMPOUNDS 1990-09-26 EP disclosed
US-4830850-A CONDITIONERS, SOFTENERS, PRESERVATIVES GAF CORPORATION (US) 1989-05-16 US disclosed
EP-0288515-A1 QUATERNIZED NITROGEN CONTAINING COMPOUNDS. GAF CORP (US) 1988-11-02 EP disclosed
WO-1988002985-A1 QUATERNIZED NITROGEN CONTAINING COMPOUNDS GAF CORPORATION (US) 1988-05-05 WO disclosed
EP-0049577-A1 Alpha-cyanophenoxybenzylamine derivatives, processes for preparing them, and their use as intermediates for the preparation of pyrethroid insecticides ICI AUSTRALIA LIMITED (AU) 1982-04-14 EP disclosed
EP-0015456-B1 OMEGA-HALOGENO-ACETOPHENONE OXIME ETHERS, PREPARATION THEREOF AND THEIR USE AS INTERMEDIATES IN THE PREPARATION OF OMEGA-AZOLYL-ACETOPHENONE OXIME ETHERS BAYER AG (DE) 1981-12-02 EP disclosed
US-4293715-A FUNGICIDES, BACTERICIDES BAYER AKTIENGESELLSCHAFT (DE) 1981-10-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11547115-B2 Wettable agrochemical composition CEL, AMY1A, PHOSPHO1 DRD4 2771/4885KMT2A 943/4885MEN1 2790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.