Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31619912 | 0.82 | ACHE (0.39) | ALDH1A1ACHEKDM4EATM | |
| SCHEMBL11526486 | 0.75 | TAS2R14 (0.38) | ARTAS2R14HSD11B1P2RX7ACHE | |
| SCHEMBL11746634 | 0.73 | CYP2A6 (0.43) | GABRA1GABRB2ALDH1A1ACHEATM | |
| SCHEMBL18397626 | 0.71 | CA1 (0.37) | ARALDH1A1ALOX12KDM4EATM | |
| SCHEMBL260225 | 0.69 | LMNA (0.36) | ARALDH1A1HSD11B1GAATDP1 | |
| SCHEMBL3821590 | 0.68 | TRPA1 (0.48) | ARGABRA1GABRB2ALDH1A1SCN8A | |
| SCHEMBL30867018 | 0.68 | TRPA1 (0.48) | ARGABRA1GABRB2ALDH1A1SCN8A | |
| SCHEMBL169124 | 0.67 | TSHR (0.47) | ARGABRA1GABRB2ALDH1A1SCN8A | |
| SCHEMBL29656610 | 0.67 | TSHR (0.47) | ARGABRA1GABRB2ALDH1A1SCN8A | |
| SCHEMBL2380334 | 0.66 | LMNA (0.46) | ALDH1A1HSD11B1GAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4132737-A | ENZYME INHIBITORS | ELI LILLY AND COMPANY (US) | 1979-01-02 | — | — | US | disclosed |