SCHEMBL115249

SCHEMBL115249

Cc1c(C(=O)c2cnn(C)c2O)ccc2c1C(C)(C)CS2(=O)=O

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29557153 1.00 NPC1 (0.30) NPC1RAB9ASMN1; SMN2
SCHEMBL15497471 0.90 SMN1; SMN2 (0.38) NPC1RAB9ASMN1; SMN2
SCHEMBL10053645 0.89
SCHEMBL1919784 0.89
SCHEMBL12770866 0.89
SCHEMBL12698598 0.88
SCHEMBL21277310 0.80 CNR1 (0.31)
SCHEMBL13184359 0.80
SCHEMBL22418746 0.79
SCHEMBL22080276 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2848125-A1 Herbicidal compositions Syngenta Limited (GB) 2015-03-18 EP claimed
EP-2326722-B1 HERBICIDE TOLERANT PLANTS SYNGENTA LTD (GB) 2014-08-06 EP claimed
US-20110173718-A1 HERBICIDE TOLERANT PLANTS SYNGENTA CROP PROTECTION, INC. (US) 2011-07-14 US claimed
EP-2326722-A2 HERBICIDE TOLERANT PLANTS Syngenta Limited (GB) 2011-06-01 EP claimed
WO-2010029311-A2 HERBICIDE TOLERANT PLANTS SYNGENTA LIMITED (GB) 2010-03-18 WO claimed
US-12610950-B2 Method for weed control in lawn or turf DISCOVERY PURCHASER CORPORATION (US) 2026-04-28 US disclosed
US-12565489-B2 Heterocyclyl pyrimidines and triazines as novel fungicides BAYER AKTIENGESELLSCHAFT (DE) 2026-03-03 US disclosed
US-12552748-B2 Pyridine (thio)amides as fungicidal compounds BAYER AKTIENGESELLSCHAFT (DE) 2026-02-17 US disclosed
US-12543738-B2 3-(pyridazin-4-yl)-5,6-dihydro-4H-1,2,4-oxadiazine derivatives as fungicides for crop protection BAYER AKTIENGESELLSCHAFT (DE) 2026-02-10 US disclosed
US-20260033493-A1 HERBICIDALLY ACTIVE COMPOUND COMBINATIONS BAYER AG (DE) 2026-02-05 US disclosed
EP-4149929-B1 TRIAZINE AND PYRIMIDINE (THIO)AMIDES AS FUNGICIDAL COMPOUNDS BAYER AG (DE) 2026-01-28 EP disclosed
US-12534456-B2 Heterocyclyl pyridines as novel fungicides BAYER AKTIENGESELLSCHAFT (DE) 2026-01-27 US disclosed
US-20080004180-A1 Novel Herbicides Based on Substituted Thien-3-Yl-Sulphonylamino(Thio) Carbonyl-Triazolin(Thi)Ones and 4-Hppd-Inhibitors BAYER CROPSCIENCE AG (DE) 2008-01-03 US disclosed
WO-2006090177-A1 USE OF 2-(2-NITRO-4-TRIFLUOROMETHYLBENZOYL)-l,3- CYCLOHEXANEDIONE IN THE TREATMENT OF PARKINSON'S DISEASE SYNGENTA LIMITED (GB) 2006-08-31 WO disclosed
US-20040162221-A1 Pyrazole derivatives and herbicides containing the same IDEMITSU KOSAN CO., LTD. (JP) 2004-08-19 US disclosed
US-20030220199-A1 Pyrazole derivatives and herbicides containing the same IDEMITSU KOSAN CO., LTD. (JP) 2003-11-27 US disclosed
US-6465395-B2 DIHYDROBENZOTHIOPHENE-SUBSTITUTED METHYLENE; CONTROL OF A BROAD SPECTRUM OF UNDESIRABLE PLANT SPECIES. BASF AKTIENGESELLSCHAFT (DE) 2002-10-15 US disclosed
US-20020115568-A1 Pyrazole derivatives and herbicides containing the same IDEMITSU KOSAN CO. LTD. (JP) 2002-08-22 US disclosed
US-20020016261-A1 Substituted methylene pyrazolinones and the herbicidal use thereof BASF AKTIENGESELLSCHAFT (DE) 2002-02-07 US disclosed
US-20020016262-A1 Pyrazole derivatives and herbicides containing the same IDEMITSU KOSAN CO., LTD. (JP) 2002-02-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12565489-B2 Heterocyclyl pyrimidines and triazines as novel fungicides CBR1, CBR3, NOX1 NPC1 1522/4885RAB9A 3667/4885SMN1; SMN2 4002/4885
US-20020115568-A1 Pyrazole derivatives and herbicides containing the same CBR3, CBR1, CYC1 NPC1 3741/4885RAB9A 1611/4885SMN1; SMN2 4844/4885
US-12610950-B2 Method for weed control in lawn or turf GHDC, WASF2, CA3 NPC1 3936/4885RAB9A 2403/4885SMN1; SMN2 3556/4885
US-20020016262-A1 Pyrazole derivatives and herbicides containing the same CBR3, CBR1, CYC1 NPC1 3741/4885RAB9A 1611/4885SMN1; SMN2 4844/4885
US-12543738-B2 3-(pyridazin-4-yl)-5,6-dihydro-4H-1,2,4-oxadiazine derivatives as fungicides for crop protection CYP4Z1, HPD, CYP4B1 NPC1 3881/4885RAB9A 3765/4885SMN1; SMN2 4178/4885
US-20080004180-A1 Novel Herbicides Based on Substituted Thien-3-Yl-Sulphonylamino(Thio) Carbonyl-Triazolin(Thi)Ones and 4-Hppd-Inhibitors HPD, DDT, TH NPC1 4467/4885RAB9A 4774/4885SMN1; SMN2 4631/4885
US-20040162221-A1 Pyrazole derivatives and herbicides containing the same CBR3, CBR1, CYC1 NPC1 3741/4885RAB9A 1611/4885SMN1; SMN2 4844/4885
US-12534456-B2 Heterocyclyl pyridines as novel fungicides CBR1, CBR3, NOX1 NPC1 1147/4885RAB9A 2835/4885SMN1; SMN2 3816/4885
US-12552748-B2 Pyridine (thio)amides as fungicidal compounds CBR1, CBR3, TH NPC1 646/4885RAB9A 2008/4885SMN1; SMN2 4770/4885
US-20030220199-A1 Pyrazole derivatives and herbicides containing the same CBR3, CBR1, CYC1 NPC1 3741/4885RAB9A 1611/4885SMN1; SMN2 4844/4885
US-20260033493-A1 HERBICIDALLY ACTIVE COMPOUND COMBINATIONS NOTUM, DDT, PPT1 NPC1 2619/4885RAB9A 3445/4885SMN1; SMN2 4640/4885
US-20020016261-A1 Substituted methylene pyrazolinones and the herbicidal use thereof DDT, DHFR, TPMT NPC1 4417/4885RAB9A 3405/4885SMN1; SMN2 4153/4885
US-20110173718-A1 HERBICIDE TOLERANT PLANTS HPD, LCT, GNPAT NPC1 3239/4885RAB9A 4244/4885SMN1; SMN2 4292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.