Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11508947 | 0.75 | NPC1 (0.46) | NPC1RAB9AUSP2TP53PKM | |
| SCHEMBL11637320 | 0.70 | NNMT (0.53) | NPC1RAB9AUSP2TP53PKM | |
| SCHEMBL4278637 | 0.65 | NPC1 (0.58) | NPC1RAB9AUSP2TP53PKM | |
| SCHEMBL7088571 | 0.64 | CTNNB1 (0.54) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL11636680 | 0.61 | NNMT (0.47) | HCAR3ALDH1A1GAA | |
| SCHEMBL51201 | 0.60 | FFAR3 (0.41) | TP53ALDH1A1 | |
| SCHEMBL1071097 | 0.60 | KCNJ1 (0.41) | USP2TP53PKMSMN1; SMN2HCAR3 | |
| SCHEMBL6468421 | 0.59 | MLYCD (0.38) | NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8053454 | 0.58 | FFAR3 (0.39) | TP53ALDH1A1 | |
| SCHEMBL4882973 | 0.58 | FFAR3 (0.39) | TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144339-A | TREATMENT OF BILHARZIASIS | RHONE-POULENC INDUSTRIES (FR) | 1979-03-13 | — | — | US | disclosed |