Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.47 |
| ▸ | MAOA | P21397 | 3/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11544488 | 0.81 | MAOB (0.50) | MAOBMAOAP2RX3CYP11B1CYP11B2 | |
| SCHEMBL11540801 | 0.78 | MAOB (0.48) | MAOBMAOAP2RX3CYP11B1CYP11B2 | |
| SCHEMBL11545463 | 0.78 | MAOB (0.48) | MAOBMAOAP2RX3CYP11B1CYP11B2 | |
| SCHEMBL22407068 | 0.78 | MAOB (0.68) | MAOBMAOAP2RX3CYP11B1CYP11B2 | |
| SCHEMBL5255602 | 0.74 | MAOB (0.52) | MAOBMAOAP2RX3CYP11B1CYP11B2 | |
| SCHEMBL11540799 | 0.73 | SCN9A (0.45) | HTR2ASLC6A4KCNH2 | |
| SCHEMBL17996051 | 0.72 | P2RX3 (0.55) | MAOBMAOAP2RX3CYP11B1CYP11B2 | |
| SCHEMBL5260362 | 0.71 | MAOB (0.49) | MAOBMAOAP2RX3CYP11B1CYP11B2 | |
| SCHEMBL16663703 | 0.71 | HTR2A (0.43) | MAOBMAOASOS1FFAR4HTR2A | |
| SCHEMBL22439721 | 0.71 | CYP11B1 (0.48) | MAOBMAOAP2RX3CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151302-A | Araliphatic dihalogen compounds composition and method of use | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-04-24 | — | — | US | disclosed |