Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11556895 | 0.87 | TP53 (0.42) | TDP1MEN1TSHRKMT2ATP53 | |
| SCHEMBL11554622 | 0.84 | GSTO1 (0.41) | TDP1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL11559959 | 0.81 | HSD11B1 (0.43) | TP53CA12CA9FABP4F10 | |
| SCHEMBL11555852 | 0.80 | MMP2 (0.49) | CA12CA9MAPTPOLB | |
| SCHEMBL11595503 | 0.76 | POLB (0.56) | TDP1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11555586 | 0.76 | GAA (0.50) | TDP1MEN1TSHRKMT2ATP53 | |
| SCHEMBL11560887 | 0.76 | CNR2 (0.53) | TDP1MEN1TSHRKMT2ACYP1A2 | |
| SCHEMBL11595388 | 0.75 | GSTO1 (0.50) | TDP1MEN1TSHRKMT2ATP53 | |
| SCHEMBL11527984 | 0.73 | GAA (0.47) | TDP1MEN1TSHRKMT2ATP53 | |
| SCHEMBL11560954 | 0.71 | CNR2 (0.55) | CA12CA9CNR2MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156732-A | Certain pharmaceutical sulfamoylbenzoyl benzofurans, benzothiophenes, and indoles | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |