Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTO1 | P78417 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 3/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11555852 | 0.86 | MMP2 (0.49) | MAPTPOLB | |
| SCHEMBL11560887 | 0.86 | CNR2 (0.53) | GSTO1MAPTACLYHTTMEN1 | |
| SCHEMBL11554724 | 0.85 | PRNP (0.45) | GSTO1MAPTPOLBHSD17B10ACLY | |
| SCHEMBL11551809 | 0.84 | TDP1 (0.43) | GSTO1MAPTPOLBHTTMEN1 | |
| SCHEMBL11559300 | 0.78 | RORC (0.43) | GSTO1MAPTPOLBHSD17B10ACLY | |
| SCHEMBL11553624 | 0.77 | CYP2C19 (0.53) | GSTO1MAPTPOLBHSD17B10HTT | |
| SCHEMBL11554345 | 0.77 | POLB (0.47) | GSTO1MAPTPOLBHSD17B10HTT | |
| SCHEMBL11553411 | 0.75 | CNR2 (0.40) | HSD17B10ACLYCMA1LMNACNR1 | |
| SCHEMBL11551530 | 0.74 | KDM4E (0.44) | GSTO1MAPTPOLBHSD17B10ACLY | |
| SCHEMBL11557882 | 0.74 | RAB9A (0.43) | GSTO1MAPTPOLBHSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156732-A | Certain pharmaceutical sulfamoylbenzoyl benzofurans, benzothiophenes, and indoles | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |
| EP-0000128-A1 | Sulfamoylaryl ketones, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-01-10 | — | — | EP | disclosed |