Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.45 |
| ▸ | MPO | P05164 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PKLR | P30613 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 7/20 | 0.41 |
| ▸ | HTR1B | P28222 | 7/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11558795 | 0.84 | HTR1D (0.47) | MPOHTR1DHTR1BHTR2A | |
| SCHEMBL11479098 | 0.84 | HTR6 (0.49) | MPOHTR1DHTR1BHTR2ASLC6A4 | |
| Hydrochloric Acid SCHEMBL11462927 | 0.83 | HTR6 (0.49) | MPOHTR1DHTR1BHTR2ASLC6A4 | |
| Hydrochloric Acid SCHEMBL11462601 | 0.83 | HTR1A (0.56) | MPOHTR1DHTR1BHTR2ASLC6A4 | |
| Hydrochloric Acid SCHEMBL11463692 | 0.83 | HTR7 (0.54) | MPOHTR1DHTR1BHTR2ASLC6A4 | |
| SCHEMBL11463974 | 0.82 | HTR2A (0.65) | HTR1BHTR2AKDM4E | |
| SCHEMBL11617630 | 0.81 | NQO2 (0.43) | NQO2PKMPKLRHTR1DHTR2A | |
| SCHEMBL11563725 | 0.80 | MPO (0.43) | MPOHTR1DHTR1BHTR2A | |
| SCHEMBL11556983 | 0.78 | SLC6A4 (0.51) | HTR2ASLC6A4 | |
| SCHEMBL11471775 | 0.77 | TRPM8 (0.53) | HTR1DHTR1BHTR2ASLC6A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147786-A | HYPOTENSIVE | CIBA-GEIGY CORPORATION (US) | 1979-04-03 | — | — | US | disclosed |