Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 6/20 | 0.47 |
| ▸ | HTR1B | P28222 | 5/20 | 0.47 |
| ▸ | MPO | P05164 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | CDK4 | P11802 | 1/20 | 0.45 |
| ▸ | CCND1 | P24385 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11479098 | 0.88 | HTR6 (0.49) | HTR1DHTR1BMPOHTR1AMEN1 | |
| SCHEMBL11563725 | 0.87 | MPO (0.43) | HTR1DHTR1BMPOHTR1AHTR2A | |
| SCHEMBL11463974 | 0.87 | HTR2A (0.65) | HTR1BHTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL11462601 | 0.87 | HTR1A (0.56) | HTR1DHTR1BMPOHTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL11463692 | 0.87 | HTR7 (0.54) | HTR1DHTR1BMPOHTR1AMAPT | |
| Hydrochloric Acid SCHEMBL11462927 | 0.87 | HTR6 (0.49) | HTR1DHTR1BMPOHTR1AMEN1 | |
| SCHEMBL11554436 | 0.84 | NQO2 (0.45) | HTR1DHTR1BMPOHTR2A | |
| SCHEMBL11559263 | 0.83 | ADRA2A (0.34) | HTR1DHTR1BMPOHTR1AHTR2A | |
| SCHEMBL11556983 | 0.81 | SLC6A4 (0.51) | HTR1AHTR2A | |
| SCHEMBL11471775 | 0.80 | TRPM8 (0.53) | HTR1DHTR1BHTR1AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147786-A | HYPOTENSIVE | CIBA-GEIGY CORPORATION (US) | 1979-04-03 | — | — | US | disclosed |