Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11554835 | 0.88 | ACLY (0.43) | TDP1CASP6GSTO1LMNAHPGD | |
| SCHEMBL11555047 | 0.86 | MMP2 (0.53) | RORCBLMMAPTPOLBCA12 | |
| SCHEMBL11554345 | 0.78 | POLB (0.47) | GSTO1LMNAALOX15MAPK1BLM | |
| SCHEMBL11553624 | 0.78 | CYP2C19 (0.53) | TDP1CASP6GSTO1LMNACYP2C19 | |
| SCHEMBL11554622 | 0.78 | GSTO1 (0.41) | TDP1CASP6GSTO1CNR1CNR2 | |
| SCHEMBL11557882 | 0.77 | RAB9A (0.43) | GSTO1LMNANFKB1MAPTKMT2A | |
| SCHEMBL11554724 | 0.75 | PRNP (0.45) | GSTO1MAPTKMT2APOLBHSD17B10 | |
| SCHEMBL11558589 | 0.75 | ALDH1A1 (0.47) | RORCTDP1CNR1CNR2GMNN | |
| SCHEMBL11553460 | 0.75 | TSHR (0.46) | CNR1CNR2GMNNLMNACYP1A2 | |
| SCHEMBL11554821 | 0.74 | MMP2 (0.50) | HPGDTSHRHSD17B10CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156732-A | Certain pharmaceutical sulfamoylbenzoyl benzofurans, benzothiophenes, and indoles | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |
| EP-0000128-A1 | Sulfamoylaryl ketones, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-01-10 | — | — | EP | disclosed |