Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 3/20 | 0.44 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11556058 | 0.87 | TSHR (0.45) | ALDH1A1MAPTCNR1CNR2HPGD | |
| SCHEMBL11555047 | 0.86 | MMP2 (0.53) | ALDH1A1MAPTBLMCA12CA1 | |
| SCHEMBL11552491 | 0.83 | ALDH1A1 (0.44) | ALDH1A1MAPTCNR1CNR2HPGD | |
| SCHEMBL1287998 | 0.78 | CYP2C19 (0.56) | ALDH1A1MAPTCNR1CNR2HPGD | |
| SCHEMBL11553411 | 0.77 | CNR2 (0.40) | CNR1CNR2LMNAMAPK1HSD17B10 | |
| SCHEMBL11555575 | 0.77 | CYP2C19 (0.62) | ALDH1A1MAPTHPGDCYP2C19LMNA | |
| SCHEMBL11552685 | 0.77 | NR4A2 (0.46) | ALDH1A1MAPTCYP2C19LMNACYP1A2 | |
| SCHEMBL11559300 | 0.75 | RORC (0.43) | ALDH1A1MAPTCNR1CNR2HPGD | |
| SCHEMBL11554821 | 0.74 | MMP2 (0.50) | ALDH1A1HPGDTSHRKDM4EHSD17B10 | |
| SCHEMBL1288011 | 0.74 | SRC (0.55) | ALDH1A1MAPTCNR1CNR2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156732-A | Certain pharmaceutical sulfamoylbenzoyl benzofurans, benzothiophenes, and indoles | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |
| EP-0000128-A1 | Sulfamoylaryl ketones, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-01-10 | — | — | EP | disclosed |