Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11558589 | 0.83 | ALDH1A1 (0.47) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL11555047 | 0.82 | MMP2 (0.53) | ALDH1A1MAPTBLMRORCCA12 | |
| SCHEMBL11551818 | 0.79 | EYA3 (0.55) | LMNACYP2C19CA12CA1CA2 | |
| SCHEMBL11556460 | 0.79 | TRPM8 (0.39) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL11555078 | 0.76 | PRNP (0.44) | LMNACNR1CNR2CA12CA1 | |
| SCHEMBL11555712 | 0.74 | EYA3 (0.55) | ALDH1A1MAPTKMT2AMEN1HPGD | |
| SCHEMBL11559300 | 0.71 | RORC (0.43) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL11556058 | 0.71 | TSHR (0.45) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL11554821 | 0.70 | MMP2 (0.50) | ALDH1A1KDM4EHPGDTSHRHSD17B10 | |
| SCHEMBL16675460 | 0.70 | HTT (0.53) | ALDH1A1MAPTKDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156732-A | Certain pharmaceutical sulfamoylbenzoyl benzofurans, benzothiophenes, and indoles | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |
| EP-0000128-A1 | Sulfamoylaryl ketones, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-01-10 | — | — | EP | disclosed |