Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11555078 | 0.86 | PRNP (0.44) | TRPM8SLC9A1CNR2CA1CA2 | |
| SCHEMBL11553411 | 0.84 | CNR2 (0.40) | SLC9A1CNR2CA1CA2CNR1 | |
| SCHEMBL11555852 | 0.83 | MMP2 (0.49) | CA1CA2CA12CA4CA6 | |
| SCHEMBL11552491 | 0.79 | ALDH1A1 (0.44) | CNR2CA1CA2CNR1CA12 | |
| SCHEMBL11551818 | 0.78 | EYA3 (0.55) | CA1CA2CA12CA9LMNA | |
| SCHEMBL11555712 | 0.73 | EYA3 (0.55) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL11554622 | 0.72 | GSTO1 (0.41) | CNR2CNR1KMT2AMEN1CYP1A2 | |
| SCHEMBL11558708 | 0.70 | MMP2 (0.46) | CA1CA2CA12CA4CA6 | |
| SCHEMBL11555382 | 0.70 | CNR2 (0.56) | CNR2CA1CA2CNR1CA4 | |
| SCHEMBL11551545 | 0.69 | STK17B (0.57) | CA1CA2CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156732-A | Certain pharmaceutical sulfamoylbenzoyl benzofurans, benzothiophenes, and indoles | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |
| EP-0000128-A1 | Sulfamoylaryl ketones, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-01-10 | — | — | EP | disclosed |